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Biomedical subjects

H S Pennypacker

Publications and source records attributed to H S Pennypacker.

16 recordsLinked to original sources

Why can't we do better breast examinations?

The professional practice of clinical breast examination (CBE) is a crucial element in early detection of neoplasms, but it is often compromised by insufficient formal training and conflicting demands on professional time. From an extensive research base, a training technology has been developed which generates highly proficient CBE. This technology is being adopted by agencies concerned with improved screening for breast cancer. New strategies for enhancing the role of CBE in breast cancer detection might include training and licensing personnel whose primary function would be to perform highly proficient CBE under professional supervision.

Breast Neoplasms↗

Key pecking during extinction after intermittent or continuous reinforcement as a function of the number of reinforcers delivered during training.

Key pecking by 7 pigeons was established and maintained on a multiple variable-ratio variable-ratio (VR) schedule of food presentation. The schedule in one of the components was then changed to fixed-ratio (FR) 1 for a predetermined number of reinforcers. Both components were then changed to extinction (i.e., multiple extinction, extinction). This sequence was repeated a different number of times for each pigeon to determine the relation between the number of reinforcers delivered during each component of the multiple VR FR 1 schedule and the number of responses during extinction. For most pigeons, there were fewer responses during extinction in the presence of a stimulus recently correlated with FR 1, regardless of the number of reinforcers received. The ratio of the total responses in extinction in the former VR component to the total responses in the former FR 1 component increased as the number of reinforcers delivered during each component of the multiple schedule increased. Within-subject replications of the partial-reinforcement extinction effect generally occurred, and there were no overall reductions in the number of responses in extinction with repeated exposures to extinction.

Animals↗

Achieving competence in clinical breast examination.

Literature documenting the breadth and quality of prevalent clinical breast examination (CBE) practice is briefly reviewed. A more thorough procedure, emphasizing training in tactile discrimination, is described and illustrated.

Breast Diseases↗

Is behavior analysis undergoing selection by consequences?

The legacy of B. F. Skinner's life is a natural science of behavior. The generality of its basic functional relations has led, by induction, to the unifying principle of selection by consequences, which accounts for morphological, behavioral, and cultural evolution. This principle both predicts and explains the observation that the science itself is becoming the object of differential selection in our culture. Public policy is increasingly being framed in terms of the effects of consequences on behavior, as illustrated by examples from education, economics, and politics. Survival of our culture may depend on our skill in managing this process.

Behavior Therapy↗

Increased proficiency of search in breast self-examination.

Two experiments were conducted to assess the relative thoroughness of three search patterns for breast self-examination (BSE). Experiment 1 compared the commonly taught concentric circles (CC) pattern to a new pattern composed of vertical strips (VS). Experiment 2 compared a radial spoke (RS) pattern to the VS pattern. Twenty-eight female subjects participated in each experiment. Each learned BSE and was post-tested using the two patterns under investigation; order of presentation was counterbalanced. BSE thoroughness was measured with the aid of a numbered grid projected on the subject's chest allowing an observer to mark each square of the grid palpated on a congruently gridded scoresheet. The percentage of the cone of the breast and of the totality of the breast tissue examined was calculated for each exam. Experiment 1 showed that the VS pattern engendered more thorough coverage of the total breast area (64.4% vs. 38.9%) and of the cone (64.1% vs. 48.7%). The results of Experiment 2 were similar: the VS pattern produced more thorough coverage of the total area (67.9% vs. 44.7%) and of the cone (70.3% vs. 57.2%). All differences were statistically reliable. Of 112 intrasubject comparisons involving the VS pattern, it produced more thorough coverage in all but nine. These results indicate that the VS pattern is the pattern of choice for maximally effective BSE.

Adolescent↗

Differential reinforcement of other behaviors to treat chronic rumination of mental retardates.

Food rumination is a maladaptive, life-threatening behavior observed among infants and institutional populations for the mentally retarded. Differential reinforcement of other behaviors (IRT greater than N) was experimentally studied as a method of reducing his behavior. Two mentally retarded clients emitted reduced rumination behaviors after implementation of the differential reinforcement procedure.

Adult↗

Improved detection of human breast lesions following experimental training.

This study was designed to evaluate the effect of breast examination training with silicone models on the detection of lesions in natural breast tissue. Six women with a total of 13 benign breast lumps were examined by 20 trainees before and after a 20--30 minute training session or a period of unrelated activity. Following the training, percentage of correct detections, duration of examination, and reports of false positives increased. Confidence in correct detections and false positives also increased, although confidence in correct detections was greater than confidence in false positives. The results indicate the effectiveness of the training and suggest a need for a more complex model for training discrimination between normal nodularity and breast lesions.

Adult↗

Effects of certain training parameters on detection of simulated breast cancer.

Forty-two female subjects, constituting 14 groups, palpated a silicone breast model in a lump detection task. Three variables, number of trials (amount of practice), search pattern requirement (restricted vs. unrestricted), and the presence or absence of lumps, were manipulated according to 3 x 2 x 2 design. The effect of all modes of practice on detection performance in posttest 1 was evidenced by an increase in percent of lumps detected and a decrease in detection threshold, but no form of practice was superior to the others. Following posttest 1 a brief search-training procedure was administered to 39 subjects which further lowered detection threshold, increased percent of lumps detected, and increased trial duration in posttest 2. The results indicate the effectiveness of the training procedure for improving detection ability and suggest the need for a more complex model to determine more specifically the effects of the practice models employed.

Adolescent↗

A multiple change score comparison of traditional and behavioral college teaching procedures.

Seventy-six students in a college-level course in human development were divided into an experimental and a control group of approximately equal size. Both groups were given a pretest composed of fill-in and multiple-choice items. The control group was exposed to conventional educational practices while the experimental group was treated in a manner similar to that described by Johnston and Pennypacker (1971), performing only on fill-in items. Post-test results showed significantly greater changes in the experimental group, regardless of the type of test item, although the difference was greater in the case of the fill-in items. The results are discussed in terms of their implications for both future research and tactics in the development of improved teaching technologies.

Journal Article↗

Transferring behavioral technology across applications.

Application flows naturally from good science, and behavioral toxicology is no exception. Phenomena discovered and procedures developed in behavioral laboratories are being applied on a wide scale in commercial, industrial, and governmental settings. In behavioral toxicology, this transfer of technology has occurred in an ad hoc manner, albeit with a degree of sophistication. The development of technology transfer in other disciplines is instructive. A symposium at the May 2001 meeting of the Behavioral Toxicology Society examined this issue, and some participants provide their contributions here. Henry Pennypacker examines the issue of whether behavioral procedures can meet the demanding standards required to transfer technology to commercial endeavors and concludes that, under some conditions, they can. He notes that the shortage of well-developed and transferred behavioral technologies results from a lack of understanding of the process of technology transfer on the part of behavior analysts. In the field of engineering, the results of basic research are transformed to candidate technologies that meet standardized criteria with respect to three properties: quantification, repetition, and verification. Kent Anger describes the challenging steps in the trail from the laboratory to wide-scale application-steps that are essential for the scaling up of any behavioral technique. Finally, Paul Mele describes the legal background to patenting and copyrighting ideas, a process that behaviorists have rarely used. Together, these topics identify the requirements and warn of the challenges and intricacies that await those who seek to transfer behavioral technology beyond the laboratory.

Animals↗