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Biomedical subjects

H S Miller

Publications and source records attributed to H S Miller.

At least 37 records · Page 2Linked to original sources
PubMed1985

Preliminary studies on the measurement of conjunctival oxygen tension in the foal.

The capability of a transconjunctival oxygen monitoring system to provide an accurate and reliable means of observing arterial oxygenation trends was evaluated in 12 horse and pony foals between 5 and 20 days of age. Ten of the foals were anesthetized with isoflurane in oxygen and nitrous oxide, and 2 foals were conscious. Inspired oxygen concentration was manipulated by differing proportions of oxygen and nitrous oxide in the fresh gas supplied to the breathing circuit. With arterial oxygen tension values ranging from less than 20 to greater than 400 mm of Hg, all foals had significant positive correlations between arterial and conjunctival oxygen tensions (P less than 0.001). Although the system seemed accurate and reliable, monitoring oxygenation in awake and mobile foals may require a ring conformer made to fit the foal's eye.

Animals↗
PubMed1976

Physiologic responses of men 49 to 65 years of age to endurance training.

A study was made of the effects of training for 30 minutes, three days a week for 20 weeks on certain physiologic measures of sedentary men between 49 and 65 years of age. Twenty-two subjects volunteered for the experimental group, and 8 others for the control group. Exercise sessions were conducted on a quarter-mile track and consisted of continuous bouts of walking and jogging. The average daily energy expenditures progressed from 228 to 365 kilocalories between weeks 4 and 20. For the same period, average exercise heart rates (HRs) progressed from 149 beats/minute (83 per cent maximum HR) to 155 beats/minute (91 per cent maximum HR). The experimental group showed significant increases in maximum oxygen intake (VO2 max) from 2.47 to 2.90 liters/minute (18 per cent) and in maximum pulmonary ventilation (VE max) from 105 to 121 liters/minute (BTPS), and decreases in resting HR, diastolic blood pressure, body weight, skinfold fat, and abdominal girth. Serum cholesterol and triglyceride levels and heart volume remained unchanged. The control subjects showed no significant changes. Regression analysis, with use of age as a covariate, showed a small but significant inverse relationship with changes in VO2 max. It was concluded that men of the 49-65 age group respond favorably to endurance exercise and show a magnitude of change similar to that found in previous investigations of similar design with younger subjects.

Age Factors↗
PubMed1975

Transient ischemic attacks due to atherosclerosis. A prospective study of 160 patients.

Patients with transient ischemic attacks (TIAs) due to atherosclerosis were studied by aortocranial arteriography. Onset of TIAs was before age 55 in 24% and between 55 and 64 in 47%. Men exceeded women by two to one. Of 160 patients, 77 were treated medically and 82 surgically. Five died in the immediate postoperative period. In the survivors, mortality has been the same in the medically and surgically managed groups. For patients with multiple lesions, surgical reconstruction of the carotid arteries was associated with very high surgical risk. In the medically treated group, anticoagulant therapy reduced the frequency of TIAs, but did not appear to protect patients from stroke. Mortality was 23% at four years, 57% of deaths being attributable to myocardial infarction and 38% to stroke.

Adult↗
PubMed1975

Frequency of training as a determinant for improvement in cardiovascular function and body composition of middle-aged men.

Frequency, duration and intensity of training have been shown to be important determinants for improving various physiological functions. This report represents a series of six training investigations conducted by the investigators over the past seven years. Within the six investigations ten separate groups were studied. These data were combined and tabulated to look at frequency of training as a determinant for improving cardiovascular function and body composition of middle-aged men. The subjects included 148 healthy, sedentary, volunteer men ranging from 28 to 64 years of age (x equal to 41). The experiments were carefully controlled and included running 30 to 45 minutes for two (four groups), three (three groups) or four (three groups) days each week for 20 weeks. The results show that all frequencies had a significant effect on cardiovascular function, but only three and four days/week regimens showed reduction in total body weight and fat. Changes in maximum oxygen consumption (VO2 max) were similar for two and three days/week programs, and significantly greater for four days. The data support the notion of frequency of training being an important criterion for improving cardiovascular function and body composition.

Adipose Tissue↗
PubMed1975

Effects of mode of training on cardiovascular function and body composition of adult men.

The purpose of this investigation was to determine the comparative effects on middle-aged men of training by running, walking, and bicycling. Sedentary men (X age = 38 yrs), who volunteered to participate, were assigned randomly to one of the following training groups: I, running (n = 9); II, walking (n = 9); and III, bicycling (n = 8). All groups trained for 30 min, 3 times/week for 20 weeks at 85 to 90% of maximal heart rate. A control group of seven men of similar qualifications also were evaluated. Training heart rates averaged 90%, 87%, and 87% of maximum for groups I, II, and III, respectively. All experimental groups improved significantly in cardiovascular and body composition measures. The former was shown by significant increases in Vo2max, VEmax, and O2 pulse and a significant decrease in resting heart rate. Body composition results showed that the experimental groups had a significant reduction in body weight, skinfold fat, and abdominal girth measurements. The control group showed no significant changes for any of the variables. It was concluded that improvement in the experimental groups was independent of mode of training.

Adult↗