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Biomedical subjects

H S Bawaskar

Publications and source records attributed to H S Bawaskar.

At least 19 recordsLinked to original sources
PubMed2000

Scorpion sting.

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Animals↗
PubMed2000

Prazosin therapy and scorpion envenomation.

BACKGROUND: 25-30% fatality due to acute pulmonary oedema in victims of Indian red scorpion (Mesobuthus tamulus) sting have been reported from Western Maharashtra, India. The advent of prazosin in recent years has revolutionized the management of severe scorpion sting cases. Majority of cases developed acute pulmonary oedema in 4-8 hours in a hospital setting irrespective of control of their arterial blood pressure with six hourly oral prazosin regimen, these cases recovered with extra dose of prazosin. We developed a standardised protocol for acute phase of treatment of these cases with the aim of preventing the development of pulmonary oedema. METHOD: We compared scorpion sting cases managed by non-protocol conventional (NPC) treatment and those by standardised protocol (SP) that included three hourly dose of oral prazosin. SP group included severe scorpion sting cases admitted to general hospital at Mahad in the year 1998 (Jan.-Dec.). While those admitted in the year 1997 (Jan.-Dec.) before the SP was implicated were the NPC group. FINDING: Characteristics on arrival of severe scorpion sting patients SP (n-17) and NPC (n-15) groups were similar that more case 6 (35%) from SP group had several hypertension on arrival. On arrival two cases from SP group and one from NPC group had pulmonary oedema. 16 (94.11%) patients from SP group recovered uneventfully, compared with 8 (53.33%) in NPC group (p-0.05). 0% Vs 5 (38.46%) developed acute pulmonary oedema (p < 0.0001) from SP and NPC group respectively, three (one had on arrival two patients during hospitalization) from NPC group had massive pulmonary oedema recovered with i.v. nitroprusside drip (SNP). While from SP group one had massive pulmonary oedema on arrival recovered with i.v. SNP, other one had pulmonary oedema recovered with oral prazosin. Cool extremities (vasoconstriction) persisted 11.5 (5-20) VS 18 (12-26) hours in SP and NPC group respectively. INTERPRETATION: Compared with NPC management; development of acute pulmonary oedema prevented by standardised protocol regimen at rural setting.

Adolescent↗
PubMed1998

Premonitory diagnostic signs and symptoms (scores) of thyroid hypofunction: a clinical observation.

We analyzed signs and symptoms of 79 cases of clinically suspected thyroid hypofunctions. There is positive correlation between clinical manifestations and thyroid stimulating hormone (TSH). In 33 (41.7%) TSH was ranged between 20-75 microunit (mu u) suggestive of hypothyroidism, 36 (45.5) were euthyroid. Clinical signs and symptoms are scored according to their frequency correlated with serum TSH are 4,3,2,1, and 0.5.

Adolescent↗
PubMed1998

Scorpion sting.

Acute life threatening systemic involvement (cardiovascular and central nervous system) occur due to scorpion poisoning, often reported from rural part of world comprises the majority of developing countries. The most serious symptoms are hypertension, impaired left ventricular systolic function, hypotension and pulmonary oedema. Scorpion antivenin neutralizes circulatory and tissue venin. It has no action on effective effectors (Receptors). Prazosin possesses pharmacological properties that render it most suitable in antagonizing the toxicological effects of scorpion venom.

Animals↗
PubMed1996

Malaria vaccine.

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