Search PubMed⌕ Search

Biomedical subjects

H Rose

Publications and source records attributed to H Rose.

At least 73 records · Page 4Linked to original sources
PubMed1986

Development of retinal arteriolar tortuosity in previously unaffected family members.

A family affected by retinal arteriolar tortuosity over a nine-year period has been observed, and the appearance of the abnormality in three previously unaffected family members in late teen-age has been documented. The proband has suffered visual loss due to optic disc infarction, this complication has not previously been reported. We believe that this is the first report of retinal arteriolar tortuosity in a British family.

Adolescent↗
PubMed1985

Barriers in cardiac substrate supply.

The capillary wall, due to its diffusional resistance, causes concentration differences between the vascular space and the interstitial space for substances which are released or taken up by the heart. Estimation of capillary transfer and interstitial concentration in isolated hearts, however, indicates a variable diffusional resistance, which in the case of glucose results from an insulin dependent transfer mechanism and in the case of lactate from a dependence of lactate transfer on lactate concentration or direction of transfer. Due to the unpredictable interstitial concentration investigation of sarcolemmal transfer appears to be possible at present only with isolated cardiac myocytes. Sarcolemmal transfer was studied for glucose and lactate. Recent investigations of lactate transfer revealed saturation kinetics, dependence on pyruvate (inhibition at low lactate concentration and enhancement at high lactate concentration) and dependence on pH (linear increase with lowered pH [8.0 to 6.7]).

Animals↗
PubMed1984

CT of thrombosed arteriovenous malformations in children.

Thrombosed arteriovenous malformations (AVMs) in children are rare lesions that may present with headaches or a seizure disorder. Thirteen patients (4 months to 21 years of age) with this lesion were examined with computed tomography (CT). In 11 patients surgical confirmation was obtained, and the other two patients were examined with follow-up CT scans. Angiography either showed an avascular mass (7/13) or was negative (6/13). CT showed a lobulated lesion (8/13), peripheral location (11/13), and minimal surrounding edema (8/13). All of the lesions were hyperdense prior to the administration of contrast material and all enhanced either slightly or not at all following contrast material administration. It is concluded that these characteristic CT features aid in making the diagnosis of thrombosed AVM. The major differential diagnosis is small intracerebral neoplasm.

Adolescent↗