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Biomedical subjects

H Romero

Publications and source records attributed to H Romero.

At least 37 records · Page 2Linked to original sources
PubMed1994

Dietary treatment of lymphedema by restriction of long-chain triglycerides.

Two patients suffering from idiopathic unilateral lower limb lymphedema were treated with a diet in which long-chain triglycerides (LCT) were drastically restricted. From the beginning of the treatment, a distinct improvement was observed in both patients, with reduction of the affected limb perimeters, decrease of edema tension, and decrease of skin turgescence. Patient A underwent weight loss, and the reduction of the diameter of the affected limb was greater than that in the nonaffected limb. In patient B, whose weight remained stable during the study, the diameter of the affected limb underwent a remarkable diminution, while no changes were detected in the nonaffected limb. To the authors' knowledge, this is the first report of dietary treatment of idiopathic lymphedema, these being preliminary results of an ongoing study in a group of patients suffering from lymphedema treated with a low LCT diet.

Adult↗
PubMed1989

Studies on antigens from agents causing black grain eumycetoma.

Culture filtrate and cellular antigens prepared from 14 agents which cause black grain eumycetoma were compared by double diffusion and immunoelectrophoresis. The fungal agents studied included five isolates of Madurella grisea, two of Madurella mycetomatis and a single isolate each of Pyrenochaeta mackinnonii, Pyrenochaeta romeroi, Chaetosphaeronema (Pseudochaetosphaeronema) larense, Plenodomus avramii, Phoma/Phyllosticta, Aureobasidium (Exophiala) mansonii and Leptosphaeria senegalensis. Cross-comparisons between all paired combinations of antigens and rabbit antisera raised against each antigen, before and after absorption with heterologous antigens, were expressed as percentage homologies. Cross-reactivity was marked (up to 90%) within the M. grisea group and between M. grisea and P. mackinnonii, but not with P. romeroi. The results suggest that the representatives of the M. grisea group tested were similar or identical to P. mackinnonii. Little antigenic similarity was observed between M. grisea and M. mycetomatis. The remaining antigens and antisera reacted most strongly with their homologous counterparts, except for L. senegalensis which had antigens in common with M. grisea (0-55% homology) and P. mackinnonii (70% homology). Analysis of the antigenic patterns derived from five of six unidentified isolates from patients with black grain eumycetoma showed marked similarity to M. grisea and P. mackinnonii.

Antigens, Fungal↗
PubMed1986

QT prolongation and torsade de pointes ventricular tachycardia produced by Ketanserin.

A 65-year-old man with arterial hypertension received oral treatment with Ketanserin, a new drug, during a period of five months. He developed marked QT interval prolongation and have several Stokes-Adams attacks. A Holter recording obtained during one of these episodes showed torsade de pointes ventricular tachycardia. The arrhythmias occurred during maximum QT interval prolongation. The correlation between Ketanserin and QT interval prolongation was evaluated by using several Holter studies during administration and withdrawal of the drug. The effect of Ketanserin on the QTc interval was analyzed retrospectively in six patients who had been taking the drug orally. Following a period of four to eight months, the QTc interval was prolonged by the drug (5 to 31%, mean 17%) in five patients. We conclude that torsade de pointes is a potential hazard of long-term treatment with Ketanserin.

Adult↗
PubMed1979

Effects of galactose, glucose and fructose on carbohydrate-lipid metabolism.

Doses of glucose, galactose and fructose were administered orally and intravenously, while monitoring the levels of blood glucose, serum insulin, free fatty acids, cholesterol and triglycerides. Blood glucose increases when glucose is administered orally or intravenously, but does not vary significantly with any other sugar. The increase in insulinemia only with oral and intravenous glucose and with oral galactose is in agreement with the participation of intestinal factors in the determination of insulin secretion. The results obtained for free fatty acids with the various sugars may be due to the metabolic properties of each sugar. We found no significant variations in the levels of cholesterol and triglycerides, perhaps because of the short duration of the experiment.

Administration, Oral↗