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Biomedical subjects

H Robbins

Publications and source records attributed to H Robbins.

34 records · Page 2Linked to original sources

Influencing mental health policy: the MHA approach.

The Mental Health Association was founded in 1909 as a citizen advocate organization for the mentally ill. Today it embraces more than a million members in nearly 850 chapters nationwide and conducts numerous programs designed to prevent mental illness, promote mental health, and improve mental health services. In recent years it has played an increasingly active role in influencing mental health policy at the federal level. This article focuses on the association's activities in the political arena.

Community Mental Health Services↗

Failure of a "prophylactic" antimicrobial drug to prevent sepsis after fiberoptic bronchoscopy.

A 53-year-old patient with lymphoblastic lymphoma developed progressive interstitial pulmonary infiltrates. The patient was believed to have Pseudomonas bronchitis and was given parenteral gentamicin. Transbronchial lung biopsy performed through a fiberoptic bronchoscope was complicated by the development of Pseudomonas septicemia. The organism isolated on blood culture, like the one isolated on sputum culture, was fully susceptible to gentamicin in vitro. A prophylactic antimicrobial drug did not prevent bacteremic Pseudomonas infection in our immunosuppressed patient with pre-existent Pseudomonas bronchitis.

Bronchitis↗

Reducing the number of inferior treatments in clinical trials.

In clinical trials comparing two treatments, one would often like to control the probability of erroneous decision while minimizing not the total sample size but the number of patients given the inferior treatment. To do this obviously requires that one use a datadependent allocation rule for the two treatments rather than the conventional equal sample size scheme, whether fixed or sequential. We show here how this may be done in the case of deciding which of two normally distributed treatment effects has the greater mean, when the variances are assumed to be equal and known. Similar methods can be used under other hypotheses on the underlying probability distributions, and will provide a considerable increase in flexibility in the design of sequential clinical trials.

Clinical Trials as Topic↗

Group practice.

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Group Practice, Dental↗