Cosegregation of balanced translocation (1;2) with retarded speech development and dyslexia.
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Biomedical subjects
Publications and source records attributed to H Remschmidt.
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This study set out to investigate the correlation between depressive symptomatology and the eating disorder psychopathology at a 3-year follow-up after discharge of 34 adolescent anorexia nervosa patients. Three standardized rating instruments were employed to assess depression and two defined outcome criteria were used to assess the eating disorder. Correlation analysis revealed that there was a consistent and significant association between the severity of eating disorder symptoms and the degree of depression at follow-up. According to the subscales of the average outcome score of Morgan and Russell (Psychological Medicine 5:355-371, 1975), depression was related more to social maladaptation than to the specific eating disorder psychopathology.
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For the first time, trance states have been included in the International Classification (ICD-10) as a separate identity. The case of a 13-year-old boy is presented and the diagnostic process discussed especially the differentiation between trance states and epilepsy. Psychotherapy and the in-patient treatment course are described including the factors facilitating a positive outcome.
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Though the concept of developmental psychopathology is broadly discussed nowadays, a real integration of the different aspects of developmental psychology, developmental neurology and developmental physiology is not yet achieved. Elements that have to be considered to arrive at such an integrative view are pointed out. Sex differences and individual differences as well as the issue of continuity and change of behavior in the developmental process, the meaning of risk factors and protective factors and prediction research have to be considered. The importance of the developmental perspective with respect to the classification of psychopathological features is stressed and the problems that arise when trying to integrate this perspective into the existing classification schemes. Finally, it is shown how--by means of logistic models--the complex interaction between very heterogeneous factors, for example the connection between biological and psychosocial influences in the developmental process, can be described.
In this paper, the main questions examined are: 1. The relationship between clinically diagnosed hyperkinetic syndrome (HKS) and 3 questionnaires for parents (Child Behavior Checklist (CBCL) by Achenbach and Edelbrock, Enzephalopathie-Fragebogen by Meyer-Probst and 10-Item scale by Conners). 2. The relationship between the clinical psychiatric diagnosis and the questionnaires and allergological parameters. In order to answer these questions, a sample of 122 psychiatric patients with "extraversive" behavior disturbances (HKS: N = 104, other "extraversive" disorders, mainly conduct disorders (EVD): N = 18) was examined prospectively and sequentially. The preliminary results are: a) The children with HKS, the children with EVD and the children with HKS and conduct disorder could be differentiated by several subscales (Especially by "introversive" symptoms) of the CBCL and the Fragebogen by Meyer-Probst. The Conners scale showed significant differences between the groups on only one item. b) The children with HKS, especially those without conduct disorder, had two to three times as many allergies as the children with HKS and conduct disorders or those with EVD.
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Selective and sustained visual attention were tested in 29 boys with developmental dyslexia and 28 normal spellers (also boys) matched for age, grade in school, I.Q. and other developmental parameters. The developmental dyslexia group had deficits in selective attention. A significant effect of task difficulty was found. There was no dysfunction in sustained attention.
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A sample of 131 consecutively hospitalized psychiatric inpatients (adolescents of 12 years and older) was investigated with regard to the question of whether family relationship variables influence therapy outcome. Before the beginning of treatment, the familial relationship structure, specifically bonding behavior and rejecting/detachment behavior in the interactions among father, mother and adolescent, was investigated. The clinical rating scales used yielded values representing directed relationship characteristics of the family triad. These relationship values were used as prognostic variables for prediction of therapy outcome, which was assessed independently of the family diagnostic ratings. The results show that the relationship dynamics in the family have a high prognostic value with regard to changes in symptoms during therapy. Several different prognostically relevant characteristics of the relationship structure could be identified.
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