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H Reichert

Publications and source records attributed to H Reichert.

At least 91 records · Page 5Linked to original sources
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Molecular correlates of neuronal specificity in the developing insect nervous system.

The development of the nervous system in insects, as in most other higher animals, is characterized by the high degree of precision and specificity with which synaptic connectivity is established. Multiple molecular mechanisms are involved in this process. In insects a number of experimental methods and model systems can be used to analyze these mechanisms, and the modular organization of the insect nervous system facilitates this analysis considerably. Well characterized molecular elements involved in axogenesis are the cell-cell adhesion molecules that underlie selective fasciculation. These are cell-surface molecules that are expressed in a regional and dynamic manner on developing axon fascicles. Secreted molecules also appear to be involved in directing axonal navigation. Nonneuronal cells, such as glia, provide cellular and noncellular substrates that are important pathway cues for neuronal outgrowth. Once outgrowing processes reach their general target regions they make synapses with the appropriate postsynaptic cells. The molecular mechanisms that allow growth cones to recognize their correct target cells are essential for neuronal specificity and are being analyzed in neuromuscular and brain interneuron systems of insects. Candidate synaptic recognition molecules with remarkable and highly restricted expression patterns in the developing nervous system have recently been discovered.

Animals↗
PubMedDate not supplied

[Experiences with ambulatory long-term blood pressure measurement in childhood and adolescence].

In a period of more than 2 years experiences with ambulatory blood pressure monitoring (ABPM) in children and adolescents aged from 2 years onward were collected, and practicability and clinical possibilities of diagnostic use were examined. We used the Medilog-ABP apparatus (Oxford Medical, Oxford Instruments Group P.L.C.), which functions fully automatically by the auscultatory method. The following results can be stated: 1. ABPM is accepted very well by young patients. Disturbances of normal behavior or sleep occurred in only 10% of the cases. 2. The rate of fault values in ambulatory long-term use is about 30%, by which useful diagnostic information is guaranteed. 3. By invasive and non-invasive parallel measurements a good validity of the values could be proved. 4. The amount of information provided by this method must be considered very great in clinical questions. ABPM allows a detailed evaluation of circadian blood pressure patterns, and an individual adjustment of circulation therapies. According to our experiences ambulatory blood pressure monitoring thus represents an enrichment of circulation diagnostics in pediatrics.

Adolescent↗