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Biomedical subjects

H Reichel

Publications and source records attributed to H Reichel.

At least 91 records · Page 5Linked to original sources

[Radiosynoviorthesis with yttrium-90-silicate. Results compared to aurum-198-colloid and whole body radiation load].

The results of the radiosynoviorthesis with yttrium-90 silicate in 36 joints, are reported. In comparison to the radiogold therapy in 64 joint, yttrium-90 was a little more effective. Additionally, the body distribution of radioactive yttrium after radiosynoviorthesis of knee joints, was measured in 6 patients. It could be shown that the uptake of the regional lymphnodes was between 4 and 5% of the yttrium administered. The radiation dose of the regional lymphnodes certainly exceeds 1000 rad. The results point to the importance of a careful selection of patients for radiosynoviorthesis.

Arthritis, Rheumatoid↗

Serum dopamine-beta-hydroxylase in psychiatric patients and normals. Effect of d-amphetamine and haloperidol.

Serum dopamine-beta-hydroxylase activity was estimated in groups of normals and of psychiatric patients, using a thin layer radiochromatographic method. The percentage of patients with schizophrenic and with depressive symptomatology was higher in the population with high enzyme activities. In addition, d-amphetamine given to normals caused an increase in the serum activity while haloperidol caused the opposite effect. The activity in serum is interpreted as a loss in the enzyme from the place it acts physiologically, with possible influence on the noradrenaline synthesis rate.

Depression↗

Time- and rate-dependence of the inotropic action of noradrenaline in the isolated guinea-pig's atrium.

UNLABELLED: The inotropic action of noradrenaline (10-6 mol/l)) was studied on a left guinea-pig's atrium which was isolated functionally by ligations and perfused during artificial stimulation (basal rhythm: 120/min) over a period of 5 to 10 hrs. Each half hour the rate was varied within a range from 60 to 300 imp/min. RESULTS: When modernaline is applied continuously throughout the experienment, contractility in terms of amplitude and rate of pressure development is almost maintained on the control level at the stimulation rates over at least 4 hrs of perfusion. When noradrenaline is applied at various stages of perfusion it compensates for the foregoing decay of contractility even after 8 hrs. Since contractility during normal perfusion decreases much more at a lower than at a higher rate the inotropic action of noradrenaline is minimal at a high rate in the fresh preparation (this means: under physiological conditions) and is fully developed only during later stages of perfusion at a low rate (which is far below the physiological range.

Animals↗