Biomedical subjects
Publications and source records attributed to H Rahbari.
We report five sporadic B-K mole syndrome-like cases. Histopathologic findings in this condition are characteristic. Clinical and pathologic diagnoses do not have to await the appearance of relatively large or malignant lesions. The dermatopathologist can alter the clinician to the occurrence of sporadic atypical mole syndrome.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Small bodies resembling bacilli which stain with acid fast techniques are observed in the secretory cells of eccrine and apocrine sweat glands. The presence of these acid fast bodies is not well known and their observation could be mistaken for infection with acid fast bacilli.
We used Rhodamin B stain in sections of normal skin, benign and malignant epithelial tumors and dermatoses. Keratin staining was uneven and showed variation in different lesions. While trichohyalin of the anagen hair follicle stained with intensity, keratohyalin granules failed to show similar reaction.
The clinical course of ninety patients with the histopathologic diagnosis of mycosis fungoides is reviewed. An attempt is made to correlate sex, age, of onset, lesion type, and form of therapy with outcome of the disease. The data indicate that mycosis fungoides affects predominantly middle-aged males. Patients developing tumors or erythroderma in middle age or later tend to have a shorter survival. More aggressive therapy is associated with shortened survival. Most deaths were due to unknown or unrelated processes and therapeutic complications. The data support the theory that mycosis fungoides can be a relatively nonaggressive cutaneous lymphoma. In an attempt to treat aggressively, we may be exposing patients to increased mortality.
Seborrhoeic verrucae (keratoses) are considered to be benign lesions. Occasional bowenoid transformation of these benign growths has not been widely recognized. Seven cases of seborrhoeic verrucae with bowenoid transformations are presented to alert the clinician and the pathologist to this occurrence.
The generality of benign epithelial neoplasias of follicular origin or with differentiation toward follicular structures is briefly reviewed. Recently delineated examples of this group are more extensively discussed.
2,126 consecutively diagnosed basal cell epitheliomas (BCE) were studied for unusual sites of occurrence. A small number of BCE occurred in unexpected locations and presented some difficulty in clinical diagnosis.
Explore the source record for details and available documents.
Two cases of recurring digital fibrous tumor of childhood are reported. Both patients were infants who had lesions on the toes or fingers. In one case the lesions recurred after surgical excision and in the other the lesions started to resolve without therapy. The histologic sections of tissue showed the intracytoplasmic inclusion bodies typical of this condition.
Large cell acanthoma (LCA), which was first introduced to the dermatologic literature in 1970 and has had no major presentation since then, is not an uncommon lesion. The lesion is a circumscribed hyperkeratotic epidermal growth with the outstanding pathologic feature being large cells. Clinical diagnoses have included several benign and malignant skin conditions. Large cell acanthoma may be related to lichen planus-like keratosis and lentigo senilis. We diagnosed 38 instances of LCA among 34,000 specimens received in our dermatopathology laboratory.
Explore the source record for details and available documents.
Sixteen cases of pruritic papules of pregnancy were collected during a 32-month period. This dermatosis was introduced to the literature in 1962 but no histopathologic study of it has been published. Histopathologic presentation of pruritic papules of pregnancy is that of toxic dermatitis. This finding is not characteristic of this condition and clinico-pathologic correlation is needed for a definitive diagnosis.
Explore the source record for details and available documents.
Verrucous growths of the genitalia in young patients are usually condylomata acuminata. In five cases this type of genital lesion, viewed by light microscopy, showed dysplastic cellular changes of Bowen disease, a diagnosis that was further confirmed by electron microscopy. Bowen disease should be included in the differential diagnosis of verrucous lesions of genitalia in young people and should be ruled out by histologic examination.
Trichoadenoma of Nikolowski is a rare benign tumor of the skin with hair follicle-like direction of differentiation. This tumor is less mature than trichofolliculoma and more differentiated than trichoepithelioma. Probably because of its rarity it has not been a well recognized tumor. We are reporting on eight cases of trichoadenoma to further define this benign growth.