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Biomedical subjects

H Putzki

Publications and source records attributed to H Putzki.

At least 37 records · Page 2Linked to original sources
PubMed1988

Tumor markers carcinoembryonic antigen, tissue polypeptide antigen, and carbohydrate antigen 19/9 in liver diseases.

The tumor markers carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), and carbohydrate antigen 19/9 (CA19/9) have been compared with regard to their sensitivity to liver diseases. All three markers have been found to be sensitive to liver diseases, but to a different degree: TPA rises the most; CEA the least. The sensitivities of TPA and CA19/9 are higher in a group of liver diseases than, for comparison, in a group of colorectal carcinomas.

Adult↗
PubMed1988

The tumor markers CEA, TPA and CA 19-9 in gastric cancer.

In gastric cancer the tumor markers CEA, TPA and CA 19-9 display relatively low sensitivity, which in relation to a specificity of 90% lies between 20% and 25%. Compared with the simple ESR method, these sensitivities are not remarkably greater. But a combination of parameters based on discriminant analysis achieves distinctly greater sensitivities.

Adult↗
PubMed1987

[Blood cell sedimentation rate--is the 2-hour value still necessary?].

In a group of patients with colorectal carcinoma and a control group the problem was investigated whether or not the 2-hour-value of the erythrocyte sedimentation rate yields additional information. The 2-h-rate of ESR turns out to have a higher sensitivity than the 1-h-value. One should, therefore, continue to measure both the 1-h- and 2-h-value of ESR.

Adolescent↗
PubMed1987

Comparison of the tumor markers CEA, TPA, and CA 19-9 in colorectal carcinoma.

In 103 patients with colorectal carcinoma carcinogenic antigen, 19-9 (CEA), tissue polypeptide (TPA) and carbohydrate antigen (CA 19-9) were measured in serum. The values determined in these patients and in a control group have been converted into specificity-sensitivity diagrams. Comparison of diagrams of the three markers showed that CEA has the greatest sensitivity in colorectal carcinoma. Different ways to enhance the sensitivity by combination of the markers have been tried. By combination, however, the sensitivity of the single markers is not essentially enhanced.

Adult↗
PubMed1987

Neopterin. A tumor marker in colorectal carcinoma?

Neopterin is compared with other tumor markers in colorectal carcinoma. Its sensitivity is clearly lower than that of CEA, TPA and CA 19/9 and is even lower than the sensitivity of the erythrocyte sedimentation rate. The ability of neopterin to discriminate between different tumor stages is also lower than that of the other markers. The discriminant analysis shows that measurement of neopterin in the serum of patients with colorectal carcinoma gives no essential additional information.

Adult↗
PubMed1987

[Diverticulosis of the jejunum and ileum].

Six cases of diverticulosis of the small intestine are reported in this paper. Described in some detail is the pathological pattern of diverticula in jejunum and ileum. There are chronic courses with recurrent complaints in the epigastric region and with malabsorption syndrome which may lead to megaloblastic anaemia, steatorrhoea, and dermatosis. Acute processes are caused by perforation, diverticulitis, and haemorrhage. Ileus can develop owing to strangulation or, in less frequent cases, owing to incarceration of enteroliths. Chronic pneumoperitoneum may be attributable to massive jejunal diverticulosis.

Aged↗
PubMed1986

Reaction of the tumor markers CEA and TPA to a surgical trauma.

The level of the tumor marker tissue polypeptide Antigen (TPA) rises distinctly after a surgical trauma. The rise begins between 3 and 6 days after operation; the elevation lasts for more than 6 weeks. Carcinoembryonic antigen (CEA) shows no comparable reaction.

Antigens, Neoplasm↗
PubMed1986

[Significance of carcinoembryonic antigen in the treatment of colorectal cancers].

Carcino-embryonic antigen (CEA) has been tested in numerous clinical studies, from its discovery in 1965. In the context of treatment for colorectal carcinoma, its importance is primarily related to early detection of recurrences following potentially curative operations. However, its value was found to be limited in primary diagnosis. In certain cases, second-look laparotomy may be indicated solely on the basis of rising CEA levels. Further clinical studies will have to be conducted under controlled conditions, with the view to finding out, if early detection of recurrences or metastasation is really beneficial to the patient in terms of extended survival.

Carcinoembryonic Antigen↗
PubMed1986

[Diagnostic error: incarcerated hernia].

Reported in this paper are 19 patients on whom incarcerated hernia had been pre-operatively diagnosed, which proved to be wrong during the operation. Various types of inflammation, including appendicitis in the hernial sac, as well as accumulation of pus in the hernial sac and abscesses, were the disorders which had led to false diagnosis in ten cases. Tumours were recorded from four patients and cysts in the round ligament of the uterus from another three, while a funicular hydrocele was detected in one patient. In one case, painful swelling through haematoma in the inguinal region had been caused by ruptured aortic aneurysm. Ultrasonographic diagnosis is recommended for all dubious cases. Surgery should be considered a preferable option in situations of lasting uncertain diagnosis, in order to avoid incarceration from remaining unnoticed.

Adult↗
PubMed1985

Nontraumatic perforations of the small intestine.

Nontraumatic perforation of the small intestine is very rarely found as a cause of acute abdominal disease. A series of 15 adult patients admitted to our hospital from 1973 to 1983 is reviewed. Underlying conditions were primary neoplasia (three patients), adhesions (three patients), intraluminal foreign bodies (two patients), metastases (two patients) and diverticulum (one patient). In four patients, the pathogenesis remained unclear (idiopathic perforations). As surgical therapy, resection and anastomosis is preferred in order to make a thorough histologic examination of the perforated bowel possible. A possible role of local drug toxicity in the pathogenesis of perforations has been discussed herein. No anastomotic leakage was observed. Four patients died (27 percent).

Adolescent↗
PubMed1985

[Endometrioses in a surgical patient sample].

In general surgery patients, endometrioses can occur in the gastro-intestinal tract; they can also appear as cicatricial endometrioses or can be manifested as other, rare localisations of endometriosis tissue. In many cases it is not possible to arrive at a pre-operative diagnosis which is histologically established. Hence, treatment in endometriosis of the colon is surgical resection in order to delineate it against carcinoma and for the purpose of treating cicatricial stenosis which is usually associated with endometriosis. In cicatricial endometrioses and cysts in the inguinal region, diagnosis became possible only after surgery and postoperative histological examination.

Adult↗