Search PubMed⌕ Search

Biomedical subjects

H Pothe

Publications and source records attributed to H Pothe.

At least 19 recordsLinked to original sources
PubMed1992

[Preoperative computer tomography and postoperative classification of brain tumors].

Imaging of different brain tumor types by computed tomography (CT) or contrast-enhanced CT scans is often very similar. Therefore, the exact preoperative CT diagnosis of intracranial neoplasms is difficult. Among 100 cases (88 primary brain tumors, 12 brain metastases), the preoperative classification by CT was correct in 51 and partially correct in 22 cases. A corresponding presumptive CT diagnosis was made in 22 brain neoplasms. 5 cases were misinterpreted. Examples of CT scans and histological pictures are compared and analysed according to the literature.

Brain Neoplasms↗
PubMed1989

[Normal cerebrospinal fluid findings in spinal tumors--an analysis of 503 cases].

Till now almost nothing has been published about normal liquor findings in spinal cord tumours. Out of 503 cases there were normal findings of total proteins and cells in 30 cases (6 per cent). A connection with the severity of the compression-syndrome was not evident. Nevertheless liquor examinations are important in diseases of the medulla spinalis. This is especially useful in the differential diagnostical demarcation of inflammable spinal cord diseases, accompanying reactions or bleedings into the spinal channel.

Cerebrospinal Fluid↗
PubMed1989

[Clinico-neurologic long-term results following surgery of intervertebral disk displacement].

Of the 1732 patients undergoing disk surgery in the period 1971-1980, a sample of 245 was selected, and data gathered prior to their operations compared with data gathered two to twelve years after the operation. Analyses was made of the specific character of pain, the state of the reflexes, motor and sensory failure, Lasègue's sign, finger-ground-distance Disorders of bladder and Rectum, and the patients' subjective judgement of their complaints. The possibility of improvement in the various findings is discussed.

Adult↗
PubMed1988

[Traumatic infraclinoid aneurysms].

Traumatic infraclinoidal aneurysms of the internal carotid artery are rare. They can occur after craniocerebral lesions and can lead to life-threatening haemorrhages from the nasopharyngeal space. Frequently it may take months after the accident before the patient experiences single or repeated rupture bleeding and is referred to acute treatment in an ENT ward. Angiography can confirm the diagnosis and is mandatory to clarify the question of collateral flow in cerebral circulation. In case of local inoperability combined with the need for a ligature of the internal carotid artery, the protective application of an extra-intracranial microvascular anastomosis is an improved safeguard against postoperative deficits. During the past five years five patients suffering from an infraclinoidal aneurysm of the carotid artery have been operated on successfully in this manner. Two of these patients suffered from a traumatic aneurysm; these two case reports are presented.

Adolescent↗
PubMed1988

Experimental studies in animals on the use of a fibrin glue from the human plasma fraction Cohn I in nerve reconstruction.

In order to compare the effects of suture and glue direct nerve connections and nerve transplantations in the sciatic nerve in rats were performed. 4, 6 and 12 weeks later, the nerve anastomosis were histologically studied. In the direct nerve connections, despite a single holding suture, dehiscences were frequently detected with the penetration of the adhesive between the nerve ends. Due to the exact adaptation with the aid of inserted nerve grafts, the anastomoses could be repaired sutureless successfully using a fibrin glue cuff. Since histologically, in comparison to suture, no foreign body granulomas were found, the findings in the literature could be confirmed. No cicatricial contractions of the anastomoses could be found. In the interfascicular nerve transplantation, comparatively good results may be obtained using the two-component adhesive on the Cohn I-fraction basis.

Anastomosis, Surgical↗
PubMed1988

Fibrin glue on the Cohn I fraction basis in repairing cerebral and dura defects--an experimental study on rats.

The rat skulls were operated upon using a trephine osteoplastically, and a defined cerebral and dura defect was induced. The repair of the cerebral defect was performed with Cohn I glue, or in combination with collageneous fleece. The dura defect was repaired by suture and/or glueing of a split skin or pedicle galeal-periostal flap. Thanks to using Cohn I glue, at all times sufficient venous hemostasis could be achieved, and in combination with collagen fleece the repair was at an optimum. The histological check-up demonstrated that neurotoxic side-effects were absent and there were no conglutinations with the dura. Suturing of the dura was highly time-consuming and impossible when the dura had been removed near the bone. The use of Cohn I adhesive permitted ready and defect repair commonly applicable. At high tension the combined suture-glueing technique proved to be superior.

Animals↗
PubMed1988

[A model for microsurgical interference of the rat cranium].

A trepanation model in the rat cranium is represented starting from the permanent enlargement of the microneurosurgical interventions with the necessity of trepanation below the microscope, the suture of the dura mater in regions with difficult access, and the dressing of cerebral tissue defects. A possibility for the microsurgical training is given for the trepanation and the dressing of dural and cerebral defects. Surgical materials and/or drugs for local application can be tested for using them in the neurosurgery too.

Animals↗
PubMed1987

[Microsurgical suture and fibrin gluing of nerve anastomoses. Animal experiment study using Cohn I human plasma fraction].

In a comparison of suture and fibrin bonding (using human plasma fraction Cohn I) direct as well as autologous and homologous nerve transplantations were performed in animal experiments. The study was carried out in a total of 66 Nn. ischiadici in Albino Wistar rats. With and without transplants the anastomoses were provided 26 times with the usual microsurgical single-button suture technique and 11 times tith a fibrin adhesive cuff with sequential application of the two components (500 I. U. thrombin/ml, 3,000 units contrycal) or simultaneous application after premixing of the components (5 I. U. thrombin/ml, 50 units contrycal). The qualitative evaluation was carried out after 4, 6, and 12 weeks according to the clinical and histological findings. With the use of sufficiently long transplants the nerve anastomoses could be fixed sutureless with the adhesive cuff more simply than with sutures. Histologically an undisturbed growing forth of the axons without foreign-body reactions and scarred constrictions could be proved. The sutured anastomoses, too, showed a good regeneration; owing to the 2-3 single button-sutures only low-degree tissue reactions occurred around the threads without any greater impairment of the proliferation of the neurites. In case of the direct uniting of the nerves adhesion was only possible in combination with a holding suture. In most cases, however, anastomose dehiscences with a bad result were nevertheless found. The direct nerve suture had to be carried out with 5-7 single-button sutures. In this case, considerably pronounced foreign-body reactions were sometimes found histologically. The nerve regeneration, however, was much better than in case of bonding by adhesion. In contrast to the application in direct nerve joining, the Cohn I adhesive could be used with good results for nerve transplantations.

Anastomosis, Surgical↗
PubMed1986

[Diagnosis and therapy of obstructions of the foramen of Monro].

Occlusions or obstructions in the region of the interventricular foramen (also known as foramen of Monro) can be due to a variety of causes. Among these are lesions of the hypothalamus that can be operated on under present-day conditions and in certain cases. This article draws attention to the possibility of choosing between several surgical approaches. Analysis of our own material (27 cases) during the past ten years shows that good results can be obtained when using modern methods of diagnosis and treatment. Four case reports are presented of four typical patients with occlusion of the foramen of Monro. If there is an associated hydrocephalus, the transcortico-transventricular approach appears to be the most appropriate one. It seems it is not always possible to effect exact type-specific separation of the diseases in the third ventricle. The presence of blood in the CSF can be a pointer toward a tumour in the third ventricle.

Aged↗
PubMed1986

[Animal experiment studies of combined suture and glue microanastomoses using a fibrin glue based on the Cohn I human plasma fraction].

A total of 48 end-to-side microvascular anastomoses between the A. and the V. femoralis of Albino Wistar rats were established with and without an additional gluing using the human plasma fraction Cohn I (Cohn-I adhesive) and clinically and histologically examined after 3-4 weeks--group 1 with 4 single button sutures and gluing, group 2 with 8 single button sutures and gluing as well as a control group with the usual suture technique with 12-14 single knob sutures (in each case 16 anastomoses). The time required for anastomosing could not be considerably reduced by the suture-gluing technique. In group 1 the thrombotic occlusion due to vascular wall dehiscences with penetration of the adhesive material into the lumen could not be prevented in eight anastomoses. Owing to the exact vascular wall adaptation with 8 single button (group 2) 14 anastomoses were free just as in the control group. Histologically the tissue-preserving influence of the gluing could be confirmed by the reduction of the number of sutures. Summarising it can be said that the perfectly performed suture technique should continue to play the dominating role, but that the combined suture-gluing technique can be a great help for the surgeon in special cases.

Animals↗
PubMed1986

[Experiences with alloplasty repair of defects of the skull calotte with modern artificial materials].

There are controversial views on alloplastic repair of skull cap defects. This has prompted the authors to report their own experience from indirect cranioalloplasty, using polymethylmethacrylates (PMMA). Seventy-two implantations were performed on patients, within 13 years, most of them for traumatic defects. Immediate repair was carried out in four cases, following neurosurgical interventions. Two implants had to be removed for cosmetic reasons and four for infections. Hence, the rate of complications amounted to six per cent. The brain-dura region was improved, accompanied by positive effects on seizure problems. Cosmetic results were good to very good in 54 patients. Ten patients could move from part-time to full-time employment, following plastic repair. Benefits and setbacks of the method are discussed.

Adolescent↗
PubMed1985

[Chronic anterior hypophyseal insufficiency following frontobasal skull fractures].

It is reported on a case of chronic insufficiency of the anterior lobe of the pituitary gland after frontobasal fracture of the skull. It is referred to the rareness of traumatically caused hypophyseal endocrine deficiency syndromes and the etiopathogenesis, the differential-diagnostic problem as well as the possibilities of a hormonal substitution therapy is discussed on the basis of the specialized literature.

Adult↗