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Biomedical subjects

H Poser

Publications and source records attributed to H Poser.

At least 19 recordsLinked to original sources
PubMed1989

Neonatal jaundice in infants of diabetic mothers.

357 IDMs and 20 healthy newborns of non-diabetic mothers were examined at term for body measurements, red blood cell count, serum bilirubin, cord blood insulin and blood glucose during the first postnatal week. The stage of maternal diabetes did not influence the course of neonatal bilirubin levels, but the IDMs had prolonged and higher bilirubinaemia compared with the controls. Hyperbilirubinaemia was found to be most prominent in newborns with an increased birthweight/length ratio and was not simply related to macrosomia (LGA). These infants had significantly lower blood glucose concentrations immediately after birth, whereas cord blood insulin was found to be identical between the IDM sub-groups. Bilirubinaemia in heavy for length infants was slightly correlated to haematocrit. For the pathogenesis of hyperbilirubinaemia in IDMs induction of heme oxygenase (due to a lack of energy provision following a phosphorylation disorder) is discussed. Nutritional support (early feeding, glucose infusions) does not affect the course of bilirubinaemia.

Bilirubin↗
PubMed1989

[Use of the new East German percentiles in the classification of newborn infants].

Re-classifying the newborns treated in the NICU of the University of Greifswald between 1983 and 1987, according to the percentiles (birthweight and length) of Lubchenco and the new standards recommended for the GDR after a data sampling in 1985, identic results could be found for the number of LGA using the 90th percentile. Certainly until the 34th week of gestation (but probably also thereafter), using the 10th percentile of the GDR standard, a to high rate (greater than 20%) of SGA infants could be found, whereas the range of birthweights of our own patients fitted exactly the distribution found by Lubchenco. The reason might be an underrepresentation of lifeborn VLBW infants in the GDR sample due to differences of the definitions used for the assessment of lifeborns and stillborns/fetal loss. Therefore, for practical use of the new standards as criterion for classifying AGA/SGA newborns until the 34th week of gestation the 5th percentile is recommended. A reevaluation of the distribution of birthweight in the GDR population is proposed including even-dead newborns in the data sampling.

Adolescent↗
PubMed1984

Evaluation of tomography and mediastinoscopy for the detection of mediastinal lymph node metastases.

In a prospective study of 88 patients seen consecutively with proven or suspected bronchial carcinoma, the validity of x-ray tomography and routine mediastinoscopy was tested for the detection and evaluation of mediastinal lymph node metastases. Positive mediastinum was defined as malignant tissue found in the mediastinum and negative mediastinum as mediastinoscopy with negative results plus a negative intraoperative mediastinal lymph node dissection. Thirty-four patients were eliminated from the analysis because carcinoma was not found or because mediastinal evaluation was incomplete by these criteria. Twenty-eight of the remaining 54 patients had mediastinal metastases. Sensitivity was 67% for tomography and 79% for mediastinoscopy. Specificity was 92% for tomography and 100% for mediastinoscopy. The differences were not significant. Sixty-six of 85 mediastinoscopies were unnecessary or unhelpful in the decision to exclude a patient from surgical intervention. Among 19 patients with lesions presumed to be inoperable based on results of mediastinoscopy (i.e., perinodal metastatic growth suspected by palpation or histologically proven), 14 patients had positive tomographic scans and 1 could not be evaluated radiographically because of right upper lobe atelectasis. We conclude that tomography of the upper mediastinum should be used to select patients for mediastinoscopy.

Adenocarcinoma↗
PubMed1983

Acute pancreatitis in obstructive jaundice following combined internal and external percutaneous transhepatic bile duct drainage (PTBD).

Percutaneous transhepatic biliary drainage (PTBD) was performed on 85 patients with obstructive jaundice. Four patients developed an acute pancreatitis after internal drainage of which one died. To our knowledge this serious complication has not yet been described in detail. These four cases are, therefore, reported and the possible causes are discussed.

Acute Disease↗
PubMed1981

[Fat embolism as a complication in shock. Clinical and therapeutic aspects (author's transl)].

In 36 patients the changes of the haemostasis in relation to hypovolaemic shock period were studied after polytrauma and or surgical operations. It was shown that a correlation between the hypovolaemic shock period and the degree of haemostatic disorder exists. The significance of this interaction for the manifestation of the fat embolism syndrome was demonstrated in two casuistics. It is concluded that the haemostatic disorder in shock enhances the development of the fat embolism syndrome. As a therapeutic consequence adequate volume substitution beside specific anticoagulation seems to be of utmost importance in the posttraumatic treatment.

Adolescent↗
PubMed1980

[Auto-suture stapler EEA in surgery of the colon and rectum [author's transl)].

The increasing use of auto-suture staplers for gastrointestinal anastomoses makes it necessary to test the value of this new method of suturing. In a "pilot study" the practicability, the tightness and permeability of the anastomosis and complications were tested and analysed in a total of 30 colon and rectal anastomoses using the EEA-suture gun. The results of 14 colon resections and 16 low anterior resections justify the further use of the EEA auto-suture apparatus and raise the question of a prospective controlled random study in which manual and mechanical machine sutured anastomoses are compared.

Colon↗
PubMed1978

[Emergency colon diagnosis by water-soluble contrast enemas (author's transl)].

When surgery of the colon must be carried out for special indications and emergencies, it is not possible to make diagnosis with Ba SO4 contrast mediums. In these cases, reasonable success can be expected with substitution of three-iodized water-soluble contrast enemas. Through perforations and discharge from the colon they are absorbed into the free peritoneal cavity and enable diagnoses which are nearly comparable in quality to those done with Ba SO4 contrast mediums. In double contrast radiography according to the Malmö technique recognition of surface detail can be considered sufficient. Advantages and disadvantages as well as indications are listed in table form. Examples are documented to complete the chapter on results.

Adult↗
PubMed1978

[Experimental microsurgery in rats (author's transl)].

Experimental microsurgical techniques using a magnifying glass and surgical microscope enable nearly all abdominal operations and organ transplantations to be performed in rats. Vascular and prosthetic segment implantations, portocaval anastomoses, heterotopic heart-, kidney-, spleen-, pancreas-, and liver transplantations some with superselective organangiography, are excellently demonstrated. Continuing research in microsurgery has considerably expanded experimental surgery and given new impulse to clinical surgery.

Abdomen↗
PubMed1977

[Bone and joint changes due to compressed air in divers and Caisson workers (author's transl)].

The radiological and morphological changes of Caisson disease in the skeleton are well known. The findings of interest to radiologists are described. Because of its position, its was possible to review a large number of divers in Kiel; these have been under observation for years, and even decades. The development, manifestation and course of chronic skeletal changes due to compressed air are described to compressed air are described and, according to severity, are classified into types 1 to 4. Late changes are discussed in detail, since these are of importance in relation to compensation.

Bone Diseases↗