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Biomedical subjects

H Pichlmaier

Publications and source records attributed to H Pichlmaier.

At least 217 records · Page 12Linked to original sources
PubMed1975

[A new organ perfusion system: Successful preservation of kidney function for 72 hrs (author's transl)].

A new preservation system is described. In this unit 17 dog kidneys were nonpulsatile perfused with hypothermic human albumin for 72 hrs and then transplanted. All kidneys started immediately to function and the PAH and inulin clearances attained normal values at least at the 7th postoperative day. The quality of the immediate function is referred to the applied perfusion pressure (20 mm Hg) and the applied temperature of the perfusion medium (7.5 degrees C). During preservation substrate utilization (oxygen, unesterified fatty acids) and the accumulation of toxic metabolic products (ammonia, uric acid) were controlled in the perfusate. Their importance concerning to the limitation of preservation time is discussed.

Albumins↗
PubMed1975

[Variations of human serum alpha-fetoprotein concentration after partial hepatectomy (author's transl)].

Alpha-fetoprotein serum concentrations were determined by radioimmunoassay in 5 patients with echinococcus involvement of the liver. In 4 cases a partial hepatectomy was possible, whereas in 1 case laparotomy had to be confined to an exposure of the liver hilus because of too many dispersed echinococcus cysts. All patients showed normal AFP levels below 20ng/ml before operation. Within the first to third postoperative day maximal AFP increases of AFP level between 2760 and 5600 ng/ml developed, which returned to normal during the following days and weeks. One patient who was submitted to strumectomy and to the same anaesthetic liver charge had no change in her normal AFP concentration. The postoperative changes of AFP level observed are interpreted as an expression of a quick and intense liver cell regeneration following the surgical treatment.

Adult↗
PubMed1975

Analysis of the optimal perfusion pressure and flow rate of the renal vascular resistance and oxygen consumption in the hypothermic perfused kidney.

Thirty-six dog kidneys were perfused with different perfusion pressures (between 15 and 60 mm. Hg) for 72 hours and then transplanted. Hypothermic human albumin was the perfusion fluid. Enzyme release, kidney weight, and renal oxygen consumption were measured during perfusion. Kidneys perfused with a flow rate of 0.8 ml. per gram per minute (21 mm. Hg mean perfusion pressure) showed the smallest increase in kidney weight and the best function after transplantation. Renal vascular resistance was independent of the level of the perfusion pressure and renal oxygen consumption was independent of the applied flow rate. It is concluded that the perfusion pressure applied with hypothermic perfusion should be as low as possible because in this way kidney damage caused by perfusion can be avoided most easily.

Animals↗
PubMed1975

[Optimum perfusion pressure, renal resistance and oxygen consumption of kidney in hypothermic pulsating perfusion].

36 dog kidneys were perfused with different perfusion pressures (between 15 and 60 mm Hg) for 72 hrs and then transplanted. Hypothermic human albumin was the perfusion fluid. Kidneys perfused with a flow rate of 0.8 ml/g/min (21 mm Hg mean perfusion pressure) showed the smallest increase in kidney weight and the best function after transplantation. Renal vascular resistance was independent of the level of the perfusion pressure and renal oxygen consumption was independent of the applied flow rate.

Animals↗