Search PubMed⌕ Search

Biomedical subjects

H Petri

Publications and source records attributed to H Petri.

At least 55 records · Page 3Linked to original sources
PubMed1982

[Exercise testing in the assessment of ventricular arrhythmias (author's transl)].

During exercise, ventricular arrhythmias may be observed in 50% of healthy subjects and up to 85% of patients with heart disease. For the quantitative as well as qualitative assessment of ventricular arrhythmias, continuous ECG (Holter) monitoring is superior to the Exercise ECG. Both methods together render a 10% increase in sensitivity over that achieved through the use of one method only. In patients with repeated ventricular tachycardias, assessment through electrical stimulation is more preferable than the use of the exercise ECG or continuous ECG monitoring. In patients with coronary artery disease, ventricular arrhythmias during exercise, depending on their incidence and complexity, may indicate a two to eight-fold increase in the likelihood of cardiac death. The reproducibility of ventricular arrhythmias during repeated exercise testing is reported between 30 and 77%. Thus, in the individual patient, the complete absence of an exercise-induced arrhythmia during treatment does not permit differentiation between therapeutic effect and spontaneous variability. Accordingly, the exercise ECG is generally not an adequate method for assessment of antiarrhythmic treatment.

Arrhythmias, Cardiac↗
PubMed1980

[The role of the doctor in the prevention of ill-treatment and punishment of children (author's transl)].

The duty of the doctor in the medical and psychosocial care of families with an environment of ill-treatment should be directed to the basic concepts of a child protection model. Interdisciplinary cooperation with advisory and therapeutic institutions and with family welfare play a decisive role here. A conflict-oriented discussion with the family whose conditions with regard to Balint groups he can learn is particularly important for the doctor in charge of such a case. Ill-treatment of children must be seen in an overlapping connection of violence towards children. In the sense of primary prevention of ill-treatment it would therefore be necessary to forbid all forms of corporal punishment of children because of the considerable psychological effects.

Child↗
PubMed1979

[Cardiac glycosides and metabolites--problems of recovery in tissue extracts. Separation of visible substance spots in the nanogram range (author's transl)].

The recovery measurements in rat tissues performed via i.p. injected radioactive digoxin derivates (3H-digoxin, 125J-digoxin derivative) showed that approximately 50% of the total glycoside content will be extracted. Thus, an addition of digoxin standards to drug-free tissues may lead to false negative determinations. By comparison of the radioactivity before and after extraction the following results were obtained: Recovery from tissues 3H-digoxin 50% 125J-digoxin 40% from serum 3H-digoxin 60% added to drug free tissue homogenates 3H-digoxin 85% After i.p. application of 15 mg/kg of beta-methyldigoxin to BD9 (Berlin)-rats the resulting tissue concentrations were extracted by Amberlite XAD-2. beta-Methyldigoxin and its metabolites digoxin and digoxinbisdigitoxide could be separated and distinguished from artifacts by fluorescence detection on HPTLC-plates with a detection limit of 60 ng/spot. Concentration determined by radioimmunoassay are in satisfactory agreement with HPTLC results.

Animals↗
PubMed1979

[The psychodynamics of violence against children (author's transl)].

It was attempted to describe some important aspects of the complicated psychodynamics of violence against children. The empirical research has still the task to solve many essential problems concerning this subject. Nevertheless we can conclude from our knowledge we gained up to now, that great attention has to be paid to the psychodynamics in all therapeutic, preventive and legislative initiatives, which concern the problem of battered child syndrom and physical punishment. This is necessary in order to focus on a symptom only, that is the flogging of children, but to influence the psychodynamic conditions as well.

Adult↗
PubMed1979

[Medical management of tachycardias (author's transl)].

Guidelines for a step-wise plan of treatment of tachycardias have been compiled based on clinical empirical experience and with the aid of surface electrocardiograms, intracardial electrograms and stimulation techniques. The plan is primarily with the aid of surface electrocardiograms, intracardial electrograms and stimulation techniques. The plan is primarily oriented with respect to the antiarrhythmic efficacy, the adverse reactions and the practicability of the respective agents. Any type of tachycardia, including premature atrial or ventricular contractions, may be regarded as indication for treatment. Treatment is not indicated only in those asymptomatic patients with rare and evanescent tachycardias and in those with less than 300 premature contractions per hour. Beta-adrenergic blockers are the drugs of choice for the persistent sinus tachycardia. Should the latter agents be contraindicated, propafenon, amiodarone or aprindine may be administered. Verapamil and/or digitalis are indicated only for suppression of paroxysmal sinus tachycardias. Atrial premature contractions are best managed with guinidine or disopyramid. An acute reduction of rapid ventricular rates associated with atrial tachycardias, atrial flutter or fibrillation can best be attained through the administration of verapamil prior to digitalis or beta-adrenergic blockers. Re-establishment of sinus rhythm and prophylactic suppression of the latter should be undertaken with quinidine or disopyramid in combination with digitalis and/or either a beta-adrenergic blocker or intravenously-administered verapamil. Verapamil is the drug of choice for initial management of AV-junctional tachycardia for which a combination with digitalis may be considered. An alternative combination is that of a beta-adrenergic blocker and digitalis. For the acute treatment of ventricular tachycardias, lidocain has proved most effective. Although ajmaline and/or propafenon may be given should no response be obtained, electrical cardioversion would be more appropriate. To prevent ventricular tachycardia or when treatment is indicated for ventricular premature beats, ajmaline, propafenon, quinidine, disopyramid or mexiletine, occasionally in combination with a beta-adrenergic blocker should be employed. Verapamil and/or ajmaline, are usually very effective for termination of reciprocal tachycardias. Ajmaline or propafenon in combination with a beta-adrenergic blocker is recommended for the prophylactic treatment of reciprocal tachycardia. In patients who additionally have bradycardia, prolonged QT-intervals or pre-excitation syndromes, the guidelines should be modified accordingly.

Anti-Arrhythmia Agents↗
PubMed1978

[Management of patients after pacemaker implanation (author's transl)].

Although pacemaker therapy is characterized by a high degree of reliability, follow-up of pacemaker patients is necessary to provide early detection of pacemaker failure and optimal setting of programable pacemakers as well as to render adequate treatment of underlying disease. The most common cause of pacemaker failure is battery depletion. In spite of the available data on the mean life-expectancy of the various batteries, the individual time of depletion cannot be predicted with accuracy. Furthermore, a defect in the electronic circuitry and/or electrode may still be rarely encountered even though technical standards are high and, occasionally, threshold elevation or lead dislocation may occur in spite of conscientious implantation technique. For patients with programable pacemakers, follow-up monitoring also enables adjustment for optimal pacemaker function. Thus, through lowering of the current or narrowing of the pulse width, the life of the battery can be prolonged or, on incrementation of these 2 parameters, an increasing threshold can be compensated for within certain limits. More important, however, is the possibility of inductive pacemaker rate changes through external programing to yield the most favorable pulse interval with respect to the underlying disease. Since, in addition to impairment of the cardiac conduction system, other disease processes are frequently presented--approximately one in three patients has coronary artery disease and almost half of the patients have congestive heart failure--follow-up visits not only serve the purpose of monitoring pacemaker function but also provide an opportunity to insure an optimal clinical condition of the patient. Accurate interpretation of pacemaker function prerequisites knowledge of the type of stimulation (fixed rate, synchronized, hysteresis, magnet rate, interference frequencies), of the battery (mercury-zinc, lihium, nickel-cadmium, isotope), of the programability (rate, current, pulse width) as well as the location of impulse capture and detection and through ascertainment of secured position of the lead and generator. While the pacemaker rate enables interpretation of the state of charge of the battery, evaluation of capture and tracing threshold permit assessment of the presence of a threshold elevation, lead dislocation, an electrode fracture or a defect in the electronic circuity. Stimulation of extracardiac muscle areas may be indicative of improper positioning and inadequate isolation of the generator, lead dislocation or lead perforation.

Arrhythmias, Cardiac↗