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Biomedical subjects

H Pesková

Publications and source records attributed to H Pesková.

At least 19 recordsLinked to original sources
PubMed1999

[Initial clinical experience with deep sclerectomy in ambulatory surgery in glaucoma].

Deep sclerectomy is a non-perforating filtering operation used in surgical treatment of open angle glaucomas. The advantage of the operation is the creation of gradual filtration due to the thin trabecular Descement membrane which reduces markedly the risk of development of postoperative complications typical for perforating antiglaucomatous operations. The authors operated at the out-patient department 10 eyes of 8 patients (age 46-81 years). Indications for deep sclerectomy was seven times primary open angle glaucoma (POAG), once capsular glaucoma and twice normotensive glaucoma (NTG). In all eyes deep sclerectomy was indicated because of decompensation of the intraocular pressure with maximum tolerated therapy before surgery. None of the eyes were operated previously. The mean value of intraocular pressure before surgery was 25.1 +/- 6.5 mm Hg. From the results ensues that in nine operated eyes the intraocular pressure at the end of the 6-month follow-up period was compensated without supplementary therapy, only in one eye beta-blockers were prescribed one month after surgery. The cause of failure of filtration was the development of superficial adherence at the site of microperforatiion of the trabecular Descemet membrane which developed during operation. The mean intraocular pressure values at the end of the investigation period were 14.3 +/- 2.8 mm Hg. In two eyes haemorrhage into the anterior chamber was observed on the first day after surgery, the blood was absorbed within 24 hours. Hypotonia in two eyes was only transient and was not associated with a change in the depth of the anterior chamber or other complications. In none of the patients a decline of visual acuity was observed. In three operated eyes a change of refraction was necessary due to discontinuation of miotics after surgery. Deep sclerectomy is a delicate microsurgical technique which calls for experience and skill of the surgeon. The most complicated task is to prevent perforation of the trabecular Descemet membrane during surgery. Provided the surgical technique is perfect, it burdens the patient less than commonly performed perforating antiglaucomatous operations and it can be implemented in the out-patient department.

Adult↗
PubMed1994

[Use of highly hydrated contact lenses for therapeutic purposes].

The paper deals with the therapeutic use of contact lenses made from a new highly hydrated material developed in the Institute of Macromolecular Chemistry in Prague. Contact lenses made from a meshed copolymer of n-vinyl pyrrolidone with acetoxyethyl meta-acrylate were applied to a group of 83 patients--a total of 87 eyes. A favourable therapeutic effect was achieved in all groups of patients--in simple traumatic erosions, superficial keratopathies, relapsing erosions, bullous keratopathies, corrosion of cornea, for mechanical protection of epithelization and in persisting ulcerations. In 71 eyes (82%) the contact lens was removed after the therapeutic effect was achieved, in 4 (5%) treatment still proceeds. In the remaining patients treatment was discontinued on account of complications, persistence of the pathological finding and frequent losses of contact lenses. In the group there was no case of complicating keratoconjunctivitis. Progressing vascularization was detected in three cases in the group with persisting ulcerations. The authors did not observe development of corneal vascularization in conjunction with application of the lens. Transient corneal oedema was revealed in the group of relapsing erosions in 6 (40%) patients and in the group of persisting superficial keratopathies in 4 (31%). The rare occurrence of inflammatory complications can be explained by the sterile application of contact lenses for the necessary length of time, the local administration of antibiotics while the defect persisted and frequent check-up examinations. Contact lenses made from the described material proved useful for therapeutic application.

Contact Lenses, Hydrophilic↗