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Biomedical subjects

H Pequignot

Publications and source records attributed to H Pequignot.

At least 19 recordsLinked to original sources
PubMed1983

[Tuberculous meningitis in adults. Prognostic factors].

Clinical and biochemical data likely to constitute prognostic factors were investigated in a retrospective study of 32 cases of tuberculous meningitis. Age appeared to be a much more important factor than the initial clinical severity of the disease and the delay of treatment. Over the age of 50 years, the mortality rate was doubled. There was no correlation between age and initial severity of the clinical picture. The number of cells and level of glucose in the CSF on admission were of no prognostic significance. CSF protein levels were higher in patients who died or developed complications than in those who made an uneventful recovery (p less than 0.05). The time required for temperature and CSF protein and glucose levels to return to normal had no prognostic value. An unfavourable or complicated course should be feared when CSF protein levels are higher than 7 g/l and in the presence of persistently low CSF glucose levels.

Adult↗
PubMed1978

[Pulmonary embolism in general medicine. Characteristics and diagnostic elements].

Natural history of pulmonary embolism observed during a 4-year period in a non-discriminayory Department of Internal Medicine, with reference to 7,843 admissions : 2 per cent of patients, 9 per cent of deaths, 22 per cent of post-mortem examinations. Value of various paraclinical examinations, more especially ECG, lung scintigraphy and determination of blood gases.

Adult↗
PubMed1978

[The heart of the nonagenarian].

Clinical, radiological and electrocardiographic abnormalities found at cardiovascular examination of 140 patients in their nineties admitted into hospital, were listed and a systematic comparison was established between 36 subjects in their nineties in a home for the aged and subjects in their eighties in the same home. Comparison with previous similar series.

Aged↗
PubMed1976

[Chyloperitoneum causing intestinal obstruction].

The two cases reported here show intestinal obstruction may occur by coagulation of lymph around the loops. They permit us to better understand the physiopathology of blockage of the lymph vessels whether congenital as in the first case or traumatic as in the second case. Traumatic rupture of the cisterns chyli is exceptional. The histological lesions observed on clamped biopsies show clearly the pathology of protein-losing enteropathy.

Adult↗
PubMed1976

[Sarcoidosis and Whipple's disease. Association? Relation?].

On the basis of a personal case in which two successive diagnoses of sarcoidosis and Whipple's disease were made at an interval of four years, the authors discuss the possible association or relationship between these two disorders, both diffuse, affecting the reticulo-histiocytic system and diagnosed on a histological basis. Review in the literature of 54 cases of Whipple's disease with pleuro-pulmonary lesions makes it possible on the one hand to associate with the latter numerous examples of extra-intestinal involvement, the histological appearance of which of a non-specific epithelioid granuloma does not indicate the diagnosis during the long pre-intestinal phase, and on the other hand to explain that during this period, the presence of pleuro-pulmonary lesions leads to an initial diagnosis of the probability of sarcoidosis. The practical consequences are as follows: The appearance of intestinal signs during "sarcoidosis" should lead to intestinal or mesenteric node biopsy to seek the macrophages with highly PAS positive cytoplasm characteristic of Whipple's disease. Their discovery necessitats long term antibiotic therapy which has recently transformed the outlook in this disease, invariably fatal in the past.

Bronchi↗