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Biomedical subjects

H Pau

Publications and source records attributed to H Pau.

At least 19 recordsLinked to original sources
PubMed1992

The significance of brown coloration with regard to lens nuclear hardness in the case of extracapsular lens extraction.

Prior to extracapsular cataract extraction, it is useful to have an indication of the nuclear hardness by means of slit-lamp microscopy. Using a fine conical probe and a miniature dynamometer, the resistance to penetration (hardness) of different colored lenses and different forms of 'senile' cataract was measured exactly. In cataracts with gray, brown, or black nucleus and sometimes a clear cortex or deep supranuclear, subcapsular or intumescent cortical opacities, distinct hardening of the nucleus was found, which reached values 3-4 times higher than in clear lenses of 80 year olds. Increasing pathological brown or black coloration of the lens nucleus is related to maximum hardness; on the other hand, maximum hardening was not restricted to brown or black coloration. In some cases we only found brownish or grayish coloration in the lens nucleus that had reached maximum hardness. We found the consistency of clear nuclei of deep supranuclear and subcapsular cortical cataracts to be the same values as those of clear lenses with clear nuclei of the same age.

Aged↗
PubMed1991

The increasing sclerosis of the human lens with age and its relevance to accommodation and presbyopia.

By means of a fine conical probe and a miniature dynamometer, the resistance to penetration of different lens layers was measured. In clear human lenses the power of resistance of the lens nucleus increases with age, mostly due to the "hardening" of the nucleus. A distinct hardening of the nucleus as opposed to the cortex has been found to occur in lenses as young as 20 years of age. This "firmness" of the lens nucleus, occurring between the ages of 20 and 60 years, coincides with the decrease in accommodation range and the onset of presbyopia.

Accommodation, Ocular↗
PubMed1979

[Angiomatosis retinae (et papillae)].

The ophthalmologic and histologic signs of an angiomatosis retinae (et papillae) are presented. Some capillaries are filled abundantly with blood while others appear completely empty. Reticular fibers, starting from the vessels, form dense networks. Large sinusoid venous connections exist between choroid and tumor.

Adult↗
PubMed1979

[Metastatic choroid tumors before and after radiation].

By means of fundus photographs of metastatic choroidal carcinomate in 20 patients it is shown that the slightly prominent yellowish-grey (rarely more intense whitish-yellow) areas appear to be either lobular, composed of various nodes, or more homogeneous and solitary. Illustrations are presented of mammary carcinomata (14x), bronchial carcinomata (3x) and uterine carcinomata (3x). The bilateral metastases, occurring in 5 cases, appear all over the eye-ground; the left eye was more frequently affected. Scarring from irradiation (or the use of cytostatics) is followed in the region of the tumour either by pure depigmentation, an almost regular patchy or punctate pigmentation, irregular displacement of pigment such as follows a severe choroiditis disseminata, or a dark, almost regular pigmentation. The X-ray radiation of a choriodal metastasis of a uterine carcinoma led to necrosis of the chorioidea, the pigment epithelium, and the peripheral retina.

Adult↗
PubMed1979

[Macular changes due to corticosteroids (author's transl)].

After fives years administration of high doses of corticosteroids, an nine-year-old girl developed a Cushing's syndrome with osteoporosis. Striate and circular pigmental fissures appeared in the macula of both eyes with opening of the circle to papilla.

Adrenal Cortex Hormones↗
PubMed1979

[Central serous retinitis or chorioretinitis (retinopathy or chorioretinopathy) and central hemorrhagic chorioretinitis (juvenile disciform macular detachment; focal hemorrhagic chorioiditis, presumed histoplasmosis) (author's transl)].

There are no clinical or etiological connections between central serous and central hemorrhagic chorioretinitis, Serous chorioretinitis is seen mostly in men; full visual acuity is regained in approx. 80% of all cases. It mainly affects subjects aged between 36 and 45. Hemorrhagic chorioretinitis affects both sexes to about the same extent and causes severe impairment of visual acuity. Both forms should be regarded as genuine inflammations (chorioretinitis centralis serosa, chorioretinitis centralis hemorrhagica), not as "pathies". Whereas the hemorrhagica disease is generally thought to be caused by inflammation, the serous form also often shows signs of inflammation such as varying leakages with inflammatory depigmentation and more frequently inflammatory protein increase (exudate) with precipitation on the posterior surface of the retina/anterior surface of the pigment epithelium.

Adult↗
PubMed1979

[Massive subretinal fat and lipoid deposits (author's transl)].

Both in exsudative retinitis (Coats disease 4 cases [presumed angioma of the chorioid in 1 case]), and in the exsudative form of senile macular degeneration (1 case), massive subretinal fat and lipoid deposits were observed. These form a yellowish central disc approximately between the upper and lower lateral retinal vessels. The centre of the subretinal depositis, and therefore the highest point of retinal detachment (3 dioptres), appears white.

Child↗
PubMed1978

[Iris diagnostics].

Explore the source record for details and available documents.

Diagnostic Techniques and Procedures↗
PubMed1978

[The therapy of Mooren's rodent ulcer (author's transl)].

Mooren's ulcer has not yet been treated successfully with drugs. Cautery, cryocoagulation, surgical diathermy, lamellar or perforating keratoplasty, and conjunctivoplasty usually have no or only little success. We have been able to cure our last five cases of Mooren's ulcer by an extensive and deep thermocoagulation both of the ulcer, the swollen corneal margins and the bordering conjunctiva. Then followed dilatation of the conjunctival vessels with Dionine and Priscol ointments.

Adult↗
PubMed1978

[Conjunctivitis lignosa -- an autoimmunity disease (author's transl)].

In a 33-year-old patient discrete conjunctivitides occured over a period of 3 years. Grey-white, fibrinous, spongy conjunctival swellings and white areas of cartilage-like consistency occured in relation with these. Microscopically these lesions showed parakeratotic cornified stratified epithelium, leukoplakias, chronic inflammation, round cell infiltrates, and vessel sprouts. Immunofluorescence showed, in the preparations incubated with antihuman compliment (C3), what could be described as characteristic for allergic vasculitis.

Adult↗
PubMed1978

[The clinical course of an embolism of a branch of the retinal artery (author's transl)].

The way in which a varying amount of blood runs past an almost obliterating yellowish-grey, homogenous "embolus" in a branch of the artery is shown. Finally although the "embolus" remained, there was an almost normal blood flow in amount. Retinal arteries running downwards showed changing vascular spasms, sometimes at the origin, sometimes further away from the central artery. This produces reversible scotomas. A small artery running nasally is sometimes better and sometimes worse supplied with blood. Temporary and permanent scotomata develop. Haemorrhages appearing here vary in extent.

Collateral Circulation↗
PubMed1977

[Lens changes occuring as a result of lowered pH (acidosis) (author's transl)].

In the lens, disorders of the metabolism occur, and, with them, active permeability (the cation pump with uptake of K and release of Na) changes to passive permeability and consequently Na ions enter with water. As a result, the lens increases in weight and a subcapsular (permeability) cataract develops. It is shown that the cattle lens in vitro increases in weight the lower the pH (6.5 greater than 7.5 greater than 8.5) of the surrounding fluid becomes. In a further experiment, 1 ml of buffered liquids with different pH were injected into the anterior chamber of the eyes of freshly slaughtered cattle. Here, too, the mechanically undamaged, untouched lens increased in weight more greatly as the pH (5.5 greater than 6.5 greater than 7.5 greater than 8.5) of the injected fluid was lowered. The significance of the lowering of the pH, e.g., in local inflammation (iritis, cyclitis, retinitis, etc.) or general acidoses (diabetes mellitus, galactosemia, hunger, extracorporeal circulation for atrophic kidney. Albright-, Love-, Fanconi-syndrome) for the appearance of incipient subcapsular clouding of the lens is pointed out.

Acidosis↗
PubMed1977

[Latticed or dendritic lines on the periphery of the retina].

Latticed or dendritic lines (true white lines) on the periphery of the retina. Vitreo-retinal adherences between the ora and equator correspond to former embryonal blood vessels to the vitreous (or retinal vessels) attaching to the retina. Between attachments of vitreous consolidations coming from in front and behind as a congenital anomaly of the retina, the latter is either loosened or replaced by connective tissue, or there is a defect, wedge-shaped from within outwards (colobomatous). These are obviously very frequently comgenital. The vitreous between and above the vitreous-retinal attachments is always liquefied and structureless. With increasing age, there is a reactive proliferation of the connective tissue (vessel-vitreous medullary cells) and pigmented epithelium. This new tissue either replaces the retina or rests on it distinctly localized, and has a strong tendency to hyalinization and sclerosis (sclerotic degenerative area). The latticed or dendritic lines (true white lines) on the periphery of the retina which for preference appear in the region of the degenerative sclerotic area sometimes consist of obliterated vessels with hyalinized walls and sometimes of hyaline connective tissue threads which are independent of the vessels. Frequently the vitreous fibre strands (vitreo-retinal adherences) may also continue through the inner retinal layers as far as these dendritic hyaline (white) retinal threads of connective tissue.

Age Factors↗