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Biomedical subjects

H Patriquin

Publications and source records attributed to H Patriquin.

47 records · Page 3Linked to original sources

Neonatal candidiasis: renal and pulmonary manifestations.

A description of three newborns with renal candidiasis and a review of 14 others suggest the following pathogenesis: antibiotic therapy in a premature baby with an intravascular catheter is followed by hematogenous renal spread, candiduria, and acute obstructive nephropathy by mycotic bezoars. The radiologic appearance is often characteristic. Prompt therapy is the only possibility for survival. Primary thoracic candidiasis occurs more frequently in the full term baby and is probably aspirated during birth. One patient is described and 20 cases from the literature are reviewed. The radiologic appearance is nonspecific.

Candidiasis↗

Necrotizing enterocolitis. Epidemic following an outbreak of Enterobacter cloacae type 3305573 in a neonatal intensive care unit.

Twelve cases of necrotizing enterocolitis (NEC) occurred within three weeks in a neonatal intensive care unit (NICU) with 325 annual admissions. Enterobacter cloacae type 3305573 was found in stool and/or blood cultures from affected babies prior to the onset of the disease. This bacterium could not be grown in cultures from infants in the same NICU six weeks later. A causal relationship between E cloacae and the epidemic of NEC is suggested.

Cross Infection↗

Ureteric hemorrhage in hemophilia with rapid healing.

A rapidly regressing ureteric hemorrhage, probably intramural, in a 14-year-old hemophiliac, is demonstrated by two closely sequential intravenous urograms. In the presence of hematuria, the intravenous urogrom outlines both the complications of hemophilia and their evolution, often directing therapy, and identifies concurrent disease.

Adolescent↗

Farmer's lung in early childhood.

A 5-year-old child with classic farmer's lung disease is reported. The disease started after a flulike episode and progressed during 3 months to severe respiratory failure. The clinical features were fatigability, weight loss, recurrent fever, dry cough, pulmonary rales, and clubbing. Serologic studies for precipitins to Micropolyspora faeni were positive. The chest roentgenogram showed a ground-glass appearance with air bronchogram. The open lung biopsy material was typical for alveolitis, with minute interstitial granulomas and obliteration of lung parenchyma. The child's condition improved rapidly with prednisone therapy and avoidance of the allergen.

Child, Preschool↗

Barium enema in chronic constipation: is it meaningful?

Seventeen pairs of pre- and postoperative barium enemas performed under fixed conditions (same preparation, filling technique, and radiographic factors) were selected from the records of a group of 62 chronically constipated patients who had undergone anorectal myectomy. Measurements at different levels of the large bowel and over-all subjective diagnosis were compared to those made in group of 26 controls. The barium enema did not aid in the diagnosis of constipation or its evolution after surgery.

Adolescent↗

A vascular necrosis of the femoral head in childhood systemic lupus erythematosus.

Four of 10 children with SLE kept under observation over the past nine years have developed avascular necrosis (AN) of the femoral head. The symptoms of AN are insidious and unpredictable and predate the radiologic diagnosis by weeks to months. In a comparison of these children with SLE, with and without AN, with a group of patients with nephrosis treated with corticosteroids and a group with glomerulonephritis treated with azathioprine, AN was related to the duration of daily steroid therapy rather than the total duration of steroid treatment; this was not true for azathioprine. The occurrence of AN in our patients while they were on alternate-day steroid therapy, or coincident with a relapse, suggests that its development is determined by underlying disease.

Adolescent↗