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Biomedical subjects

H Pariser

Publications and source records attributed to H Pariser.

4 recordsLinked to original sources
PubMed1989

Syphilis.

The incidence of syphilis is higher than it has been in over 30 years with over 35,000 new cases reported in 1987. Despite this, the teaching of this disease has largely been ignored in medical schools, resulting in a very low index of suspicion by the medical profession. This article has reviewed the salient clinical features, the laboratory tests used in the diagnosis and tests of cure, and the treatment schedules, both the well-documented and those still to be evaluated. Recent disturbing facts have emerged in patients with HIV infection who also have syphilis. In these individuals the serious "late" manifestations, such as involvement of the central nervous system, may occur with greater than expected frequency and appear earlier in the course of the disease than usual. The humoral response on which the diagnostic tests are based may be altered or absent, and the response to treatment may not be as effective as that obtained in an immunocompetent individual.

Humans↗
PubMed1976

Asymptomatic gonorrhea.

The results of our studies showed that: 1. Asymptomatic gonorrhea occurred in about 70% of infected women, and in 10 to 15% of infected men; 2. Asymptomatic rectal gonorrhea occurred in 15% of those women with positive cervical cultures, and in 20% of infected women was the sole site of a positive culture; 3. The rectal site should be examined for N. gonorrhoeae both in diagnosis and in testing for cure; 4. Pharyngeal gonorrhea occurred in 22% of patients who were named as gonorrhea contacts and practiced fellatio. In 13% of this group (four cases) the pharynx was the only site of a positive culture.

Female↗
PubMed1975

Precocious noduloulcerative cutaneous syphilis.

A man had widespread, noduloulcerative syphilitic lesions that appeared, chronologically, during the "secondary" stage of syphilis. There were no systemic manifestations of the disease, except for possible periostitis. The darkfield examination and spinal fluid examinations were negative for syphilis. It is suggested that the term "malignant" syphilis should be discarded in favor of nonduloulcerative cutaneous syphilis.

Adult↗