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Biomedical subjects

H Péquignot

Publications and source records attributed to H Péquignot.

At least 19 recordsLinked to original sources

[Drug-induced complications and professional responsibility].

The authors collated the drug-induced side effects reported by subscribers to the malpractice insurance company, Sou Medical. The figures give an idea of the frequency of such events but their reflection of reality should not be overestimated. These presumed incidents represent only 9% of the reports filed (approximately 300 in 20 yr), thus showing their relative rarity. Radiological dyes and general anesthetics comprise two separate groups, as do the exceptional reactions to vaccines. Antibiotics, neuroleptics, non-steroidal anti-inflammatory drugs and corticoids are most frequently implicated, while anticoagulants are rarely cited. These findings underline the rarity of litigation for drug-induced side effects.

Adrenal Cortex Hormones↗

[Sarcoidosis at the Cochin University Hospital Center from 1975 to 1982].

An analysis of 80 cases of sarcoidosis admitted to the departments of respiratory medicine (36), rheumatology (19) and internal medicine (25) over a 7 year period, revealed a wide range of clinical presentations; there was a higher incidence of associated disease and a greater number of localisations of the disease in patients admitted to the department of internal medicine than in those admitted to the other two departments. On the other hand, bronchial biopsy was more commonly positive in patients admitted to the department of respiratory medicine whose respiratory function was more disturbed than the patients in the other two departments. The patients referred to the departments of rheumatology and internal medicine without radiological respiratory involvement had respiratory function tests and positive alveolar lavages. The prognosis was the same in all three departments; 50 p. 100 were treated with steroids. The recruitment of the patients in this series allows a different evaluation of the disease compared to series reported from more specialised departments.

Adolescent↗

[A simple evaluation of osteoporosis: study of the architecture of the upper extremity of the femur by pelvic radiography].

From the study of the architectural features of the system connecting the neck to the femoral diaphysis on pelvic radio-grams, osteoporosis can be classified into seven stages (7 to 1) of increasing severity. It is thus possible to estimate the risk of fracture, the latter being over 50 per cent from stage 4 onward. The cortex-diaphysis relationship (RCD) follows a parallel course but is less reliable. The investigation of a control group of 20 subjects and 37 patients with osteoporosis, aged 50 to over 80, shows the value of this method, with which it is moreover possible to check the evolution of the disease and the effects of treatment.

Aged↗

[The role of pericardial pathology in internal medicine].

In the multiple pathology of a non-specialised patient group in internal medicine, 1,2% presented with a pericardial disorder. The true occurrence rate of pericarditis is in fact much higher since if the cases where pericarditis is found only at autopsy are taken into consideration, pericardial involvement is found in almost 10% (this figure is higher, for obvious aetiological reasons, than that for non-fatal peridarditis). The improvement in obtaining a positive diagnosis of pericarditis is obvious when a study carried out ten years ago is reviewed. Finally, comparison of the aetiological types in our study with those seen in cardiology services shows important differences and takes account of the special nature of pericardial pathology in general medicine and the interest of its study.

Aged↗