Biomedical subjects

H P Lipp

Publications and source records attributed to H P Lipp.

3 recordsLinked to original sources

PubMed1978

Aggression and flight behaviour of the marmoset monkey Callithrix jacchus: an ethogram for brain stimulation studies.

The aggressive and flight behaviour of the common marmoset monkey (Callithrix jacchus) is described and split into behavioural units, allowing analysis of agonistic behaviour evoked by electrical stimulation of the hypothalamus. The social context of the described units is also considered. C. jacchus shows clearly recognizable behavioural patterns. Free-born animals are very timid and show typical flight reactions. Within aggressive behaviour, two types of aggression can be distinguished: very violent attacks causing severe injuries, often accompanied by particular threat displays and observed during dominance and territorial encounters, and, on the other hand, relatively harmless short attacks, together with a noisy vocalization, for defensive purposes or keeping group members at a distance.

Aggression↗

PubMed1978

Threat, attack and flight elicited by electrical stimulation of the ventromedial hypothalamus of the marmoset monkey Callithrix jacchus.

In order to elucidate whether relatively primitive primates show a similar topological organization of substrates mediating defense and flight within the ventromedial hypothalamus as has been found in other mammals, 15 marmosets (Callithrix jacchus) were chronically implanted with a total of 57 electrodes for electrical stimulation. Experiments took place in a familiar environment and under systematically altered conditions. All anatomical sites yielding vocal threat and short attacks were found to be situated in the n. ventromedialis. Flight was elicited from a region immediately lateral to this nucleus and from sites in the posterior hypothalamus. Thus, it appears that the topological organization of defense and flight behavior in cat, oppossum and marmoset are essentially similar.

Aggression↗

PubMedDate not supplied

Differential hypothalamic self-stimulation behaviour in Roman high-avoidance and low-avoidance rats.

Monopolar electrodes were implanted bilaterally and symmetrically into a small well defined region of the posterior lateral hypothalamus in 11 rats of the selected strains Roman high-avoidance (RHA/Verh, 6 animals) and Roman low-avoidance (RLA/Verh, 5 animals). Intracranial electrical stimulation (ICS) was used to study possible strain difference with respect to self-stimulation behaviour. Using a shuttle-box, the experimental set-up allowed measurements of the animal's preference, aversion, neutrality or ambivalence towards the stimulus. For both rat strains 10 electrode sites were tested with identical stimulation currents (100-600 microA in increments of 100 microA). Significant differences between the selected strains were found for preference (self-stimulation) and aversion: RLA/Verh-rats showed self-stimulation at lower stimulation currents than RHA/Verh-rats. At higher currents, both strains showed similar self-stimulation performance. RLA/Verh-rats escaped more often from ICS yielding self-stimulation at five of the six current levels. It is concluded that, in comparison with the RHA strain, RLA/Verh-rats are more sensitive to aversive effect of lateral hypothalamic stimulation. This seems to be associated with an increased sensitivity to the rewarding effects of such stimulation.

Animals↗