Biomedical subjects
Publications and source records attributed to H P Huber.
The severity of acne correlates with the quotient of triglycerides to free fatty acids in sebum. This quotient increases during systemic therapy with doxycycline, while the clinical picture of the disease improves.
Cells in Area 18 of awake and behaving cats were tested for directional preference with a large visual noise pattern. Upper and lower layer cells were found to exhibit different anisotropies for movement direction, offset by 90 degrees. These findings could reflect different functions for the global mapping and processing of optic flow field in upper and lower layers.
A group of 31 patients whose mandibles had been augmented surgically with various methods using hydroxylapatite granules between 1984 and 1987, were followed-up to rate their subjective and objective masticatory function. The subjective assessment of the treatment result is comparable to the opinion given about vestibulo- and floor of the mouth-plasty. Masticatory function determined according to the method of fractionated sieving of the chewed food did not show any significant differences from the function measured in complete denture patients with strong alveolar bones. The need for regular follow-up is emphasized.
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Research in the field of behavioural medicine concerning psychological preparation for surgery is beginning to focus on practical issues. In the first study sixty children between the ages of 4 and 8 received the usual medical preparation from the hospital staff. In addition, the patients of two treatment groups were provided with relevant information by presenting a photographic peer model, or received emotional support by a psychologically trained supervisor. The second study was designed to assess the anxiolytic effects on preoperative state anxiety in 40 adult in-patients by implementing a systematic desensitization program. As a main result the findings demonstrated the sensitizing effects of psychological preparation for surgery both in children and adults. Contraindications and resulting practical issues are discussed.
The efficacy of Clotrimazol cream paste containing a penetration enhancer in the treatment of acne vulgaris was objectified by investigating the sebum composition. Following treatment over three and six weeks, the ratio of triglyceride to free fatty acid significantly increased, which indicated an effective reduction of the lipase activity of Propionibacterium acnes within the sebaceous follicle.
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A phonetic and relaxation method combined with teleoradiography was used to measure the interocclusal interval in five subjects. The action potential of the left and right masseter muscles were derived while the subject was drinking liquid. After fitting each subject with a Shore bite path plate which reduced the interocclusal interval to 0 mm, the same experimental procedure was carried out. No significant differenced could be established using a unidirectional lead with pseudointegration. In spite of the extremely small sample, the results tend to indicate that resting suspension changes corresponding to the vertical dimension.
A double-blind trial was performed with 30 male students of the University of Düsseldorf. The volunteers were divided at random into two groups containing 15 subjects each. One group received 1-(m-methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal), and the other placebo. The latter served as the controls. On three occasions at regular intervals in the course of one week the volunteers were questioned on the basis of Janke and Debus's "Eigenschaftswörterliste" (EWL) (attribution word list). The interviews were carried out 1 h after the injection (1 ampoule 100 mg i.m.). The results in the sense of any euphoretic or dysphoretic effects are discussed.
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