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Biomedical subjects

H Ozen

Publications and source records attributed to H Ozen.

153 records · Page 9Linked to original sources

Thyroid metastasis of renal cell carcinoma. A case report.

In this article thyroid metastasis in a patient who was operated 11 years ago for renal cell carcinoma is reported with the review of the literature. That case was also the first and the only thyroid gland metastasis in 4.124 thyroidectomies during a 17-year period at our department. Because the thyroid gland may be the only and a rare metastatic site, differentiation of the metastatic lesion from the primary thyroid neoplasm could be difficult.

Carcinoma, Renal Cell↗

Moyamoya disease and alternating hemiplegia. A report of two cases.

Moyamoya disease is one of the cerebrovascular disorders and is characterized by bilateral stenosis or occlusion of the distal internal carotid arteries and their main branches. Repeated ischemic episodes in children and intracranial hemorrhage in adults with moyamoya disease is usually noted. In this report, we describe two children with moyamoya disease who presented with alternating hemiplegia. The final diagnosis was made by cerebral angiography and cranial computed tomography in these patients. Other neurological and radiological features of the patients were described.

Cerebral Angiography↗

Cardiac arrest: an unusual side-effect of intravenous ornidazole.

Nitroimidazoles have been used alone or in combination with other antibacterial agents in the treatment of brain abscess. They are associated with certain adverse reactions related primarily to the gastrointestinal tract and central nervous system. But, as far as we know, cardiac arrest due to ornidazole has not been reported in the literature. In this study, we presented a case in which cardiac arrest occurred as an unusual side-effect of intravenous ornidazole administered to a ten-year-old girl suffering from brain abscess.

Anti-Bacterial Agents↗

Comparative therapeutic results of penicillin plus chloramphenicol versus ampicillin plus sulbactam in childhood meningococcemia.

Fifty-seven cases of meningococcemia were evaluated retrospectively. The age of the patients ranged between 2 and 17 years. Of the 57 patients investigated for the efficacy of antibiotic treatment, 31 (54.4%) were treated with benzylpenicillin plus chloramphenicol and 26 (45.6%) with ampicillin plus sulbactam. Patients with criteria for a poor prognosis (presence of disseminated intravascular coagulation, low arterial blood pressure, and altered consciousness) were divided equally into two treatment groups. There were no statistically significant differences between the two treatment groups except for the higher incidence of convulsion in the group given penicillin plus chloramphenicol. The mortality rate was 19.3 percent for patients treated with benzylpenicillin plus chloramphenicol and 7.6 percent for patients treated with ampicillin plus sulbactam (p = 0.19; overall mortality rate 14%).

Adolescent↗

Salmonella typhi infections. A 10-year retrospective study.

Enteric fever is still a common health problem in many countries, especially in children. Thus a ten-year retrospective study was carried out to evaluate the clinical and laboratory properties of enteric fever and the incidence of antimicrobial resistance in children. Throughout the past 10 years, Salmonella was isolated in 105 patients by blood culturing, 27 of which were Salmonella typhi. Most of the patients were above the age of two. Besides the typical symptoms and signs of enteric fever, 29.2% of the patients had some neurologic findings. Besides, 68.5% had elevated liver enzymes while only 44.4% had hepatomegaly with or without splenomegaly. Anemia was present in 44%, leukopenia in 16% and leukocytosis in 11.1% of the cases. The emergence of antimicrobial resistance during the last five years against ampicillin, chloramphenicol and trimetoprim-sulfamethoxazole has created a challenge in treating these infections.

Adolescent↗

Congenital chloride diarrhea in a Turkish boy.

Congenital chloride diarrhea (CCD), first described in 1945, is a rare, autosomal-recessively inherited disease. It is characterized by chronic, watery diarrhea with a high fecal chloride concentration, hyponatremia, hypokalemia, and hypochloremic metabolic alkalosis. In this report, a 7.5-year-old boy with CCD diagnosed by high fecal chloride concentration is presented. Until now CCD had not been reported from Turkey, although consanguineous marriages are common.

Child↗

False aneurysm of the brachial artery in an infant following attempted venipuncture.

False aneurysms have rarely been described in the pediatric age-group. Here a case of false aneurysm of the brachial artery following accidental arterial puncture at the site of attempted venipuncture is reported. Having obtained vascular control with digital compression, the arterial repair was performed by direct suture technique. The characteristics and differential diagnosis of false aneurysms are described. The majority of false aneurysms occur as complications of percutaneous catheterization.

Aneurysm, False↗

Long-term follow-up of hepatitis B virus carriers with normal transaminases levels.

There has been very little data recorded on the natural course of chronic hepatitis B virus infection in asymptomatic children. In order to assess the natural course of liver disease in hepatitis B surface antigen (HBsAg) carriers with normal liver tests, 124 such children (81 males, 65.3%) were followed for six to 144 months (mean 36.8 +/- 22.8 months). Liver tests and hepatitis B virus (HBV) markers were tested at least every six months. In the beginning, hepatitis B e antigen (HBeAg) was positive in 61 (53%) of the 115 carriers of HBsAg who were tested. Anti-HBe was positive in 51 (44.3%), and both HBeAg antigen and anti-HBe were negative in three (2.7%) carriers. The prevalence of HBeAg was not affected by the patient's age or sex. During follow-up, 11 patients (18%) lost HBeAg (a mean annual clearance rate of 5.8%), and 12 patients (9.7%) lost HBsAg (a mean annual clearance rate of 3.1%). We found no difference in the clearance of HBsAg and HBeAg by age and sex. The presence of another HBsAg positive person in the family affected HBsAg clearance rate but not HBeAg clearance. Only seven patients (5 HBeAg positive and 2 anti-HBe positive) developed transient elevations in liver transaminases. Three of five HBeAg positive children cleared HBeAg after transaminases elevations. Of the five patients who underwent percutaneous liver biopsies, non-specific changes were found. It is concluded that hepatitis B carriers with normal liver tests should be followed with liver function tests alone and that long-term prognosis is good.

Carrier State↗