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Biomedical subjects

H Ohya

Publications and source records attributed to H Ohya.

25 records · Page 2Linked to original sources
PubMed1987

Sunlight supply and gas exchange systems in the microalgal bioreactor.

The bioreactor with sunlight supply system and gas exchange systems presented here has proved feasible in ground tests and shows much promise for space use as a CELSS device. Our chief conclusions concerning the specification of total system needed for a life support system for a man in a space station are the following. (1) Sunlight supply system: compactness and low electrical consumption. (2) Bioreactor system: high density and growth rate of chlorella. (3) Gas exchange system: enough for O2 production and CO2 assimilation.

Air Conditioning↗
PubMed1987

The applicability of catalytic wet-oxidation to CELSS.

The wet-oxidation catalysis of Au, Pd, Pt, Rh or Ru on a ceramic honeycomb carrier was traced in detail by 16 to 20 repetitive batch tests each. As a result, Pt or Pd on a honeycomb carrier was shown to catalyze complete nitrogen gasification as N2. Though the catalysts which realize both complete nitrogen gasification and complete oxidation could not be found, the Ru+Rh catalyst was found to be most promising. Ru honeycomb catalyzed both nitrification and nitrogen gasification.

Bioreactors↗
PubMed1986

Neuroendocrine regulation of LHRH and gonadotropin.

Analysis of gonadotropin secretion patterns throughout the menstrual cycle revealed a complex rhythm. Especially at 1-3 hour intervals this was seen, with a frequency that was dependent on the phase of the menstrual cycle. There is little information available concerning the role of plasma luteinizing hormone-releasing hormone (LHRH) in the regulation of donadotropin secretion in amenorrheic and postmenopausal women. In this paper, the authors present the results of a detailed investigation into the secretory pattern of LH, follicle stimulating hormone, and LHRH in normal women with a normal menstrual cycle, amenorrheic women, and postmenopausal women.

Amenorrhea↗
PubMed1984

Survey of CELSS concepts and preliminary research in Japan.

Many agricultural and other experiments relating to the development of a Controlled Ecological Life Support System (CELSS) were proposed by scientists throughout Japan in the fall of 1982. To develop concrete experimental concepts from these proposals, the engineering feasibility of each proposal was investigated by a CELSS experiment concept study group under the support of the National Aerospace Laboratory. The conclusions of the group were described in two documents. Originally, the study group did not clearly define necessary missions leading to the goal of an operational CELSS for spaceflight. Therefore, the CELSS experiment concept study group met again to clarify the goals of CELSS and to determine three phases to achieve the goals. The resulting phases, or missions, and preliminary proposals and studies needed to develop a CELSS are described herein.

Animals↗
PubMed1983

[Suppression of puerperal lactation by metergoline].

Suppression of puerperal lactation by a potent serotonin antagonist, metergoline was studied in 33 puerperal women, i.e., abortion after sixteen weeks of gestation 6, premature labor 13, labor at term 13, and hydatiform mole 1. The drug was administered orally at a dose of 4 mg bid for 5 days to 26 subjects, starting within one week from delivery (group A). The remaining 7 subjects received 4 mg of metergoline bid for 7 days after more than 2 weeks from delivery (group B). Lactation was either rapidly suppressed or prevented in 22 out of the 26 subjects in group A and in all subjects in group B. After the therapy was stopped, rebound phenomena were observed in 4 subjects in group A and in 2 subjects in group B, but a further 5-7 days' treatment with metergoline produced satisfactory results. The mean plasma prolactin levels, studied in 10 subjects in group A at hourly intervals after the first metergoline dose, decreased significantly one hour later (p less than 0.05) and reached the nadir level, 19.9 +/- 2.6% of the mean basal value, 4 hours later. The daily plasma prolactin levels in 9 subjects were significantly lower than those of the control group during metergoline treatment (p less than 0.001). No side effects of metergoline medication were observed. Metergoline for a short course of administration is very effective in the suppression of puerperal lactation. In case of the suppression of lactation after the second week of puerperium, 10-14 days of metergoline treatment is recommended to avoid the rebound phenomena.

Adult↗
PubMedDate not supplied

Effects of ethanol on the stress-induced expression of NGFI-A mRNA in the rat brain.

We investigated expression of NGFI-A/zif268 mRNA, reliable marker for neuronal activation in response to stress in the brain of rats pretreated with ethanol. The rats were orally administrated with either 25% sucrose or 20% ethanol (20 ml of kg body weight) 10 min before the onset of the stress. The rats were exposed to immobilization stress for 20 min and quickly decapitated. The brains were extracted and immediately frozen. The level of NGFI-A mRNA was evaluated by in situ hybridization histochemistry. Prior ethanol administration attenuated the immobilization stress-induced upregulation of NGFI-A mRNA level in the neocortex and hippocampus. However, in the paraventricular hypothalamic nucleus, prior administration of ethanol did not affect the upregulation of this gene. These data suggest that ethanol abolishes the forebrain component of the stress response while it fails to attenuate the stress response on a region of the brain that regulates the autonomic nervous system and the hypothalamo-pituitary-adrenal axis. Regional differences in the expression of NGFI-A mRNA may be important for the complex interactions between ethanol and stress.

Animals↗