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Biomedical subjects

H Ohashi

Publications and source records attributed to H Ohashi.

At least 577 records · Page 32Linked to original sources
PubMed1976

Some comments on the urethral syndrome.

In three-quarters of the patients with urethral syndrome, chronic urethritis was found endoscopically. Of the remainder some precentage could be said to have a psychosomatic disorder. Therefore, the patients with unexplained urethral syndrome were unexpectedly few. Although urethral syndrome attacks adult females of all ages, the incidence was highest in the middle age range. Against this, chronic bacterial cystitis was spread evenly over the entire age range. The urethra was rather narrow in women with urethritis, but of normal size in those without urethritis, even if they had urethral syndrome. A satisfactory result was obtained through the topical administration of steroid solution, even where general treatments, including the use of antibiotics, have failed.

Age Factors↗
PubMed1976

Cystic goiter with squamous-cell metaplasia--case report and comment on origin of squamous-cell cyst.

A 53-year-old woman with a left unilocular cystic goiter of the size of a small orange was reported. Approximately four-tenths of the innter surface was lined with several layered squamous epithelium with few follicles remaining. A gradual metaplastic transition from the follicular epithelium to the flattened cuboidal and to the squamous epithelium was observed. The ultimobranchial body has been understood to be a possible origin of an entirely squamous cell cyst of the thyroid, three of which have been reported. The difference between the ultimo-branchial and metaplastic origins will be discussed, and a new designation-primary (ultimo-branchial) and secondary (metaplastic) squamous-cell cyst will be proposed.

Animals↗
PubMed1971

The relative contribution of K and Cl to the total increase of membrane conductance produced by adrenaline on the smooth muscle of guinea-pig Taenia coli.

1. The relative contribution of K and Cl to the total increase of membrane conductance produced by adrenaline on the smooth muscle of guinea-pig taenia coli has been investigated. Constant current pulses were applied with a pair of large external electrodes, the voltage change was recorded with an intracellular micro-electrode, and the change in the size of the electrotonic potential by adrenaline was measured.2. Adrenaline hyperpolarized the membrane by about 8 mV with a range from 5 to 15 mV and it reduced both the size and the time course of the electrotonic potential. On the average the size was reduced to 65 +/- 1.8% (n = 75) of the normal size, from which a decrease of the membrane resistance to 45 +/- 2.2% was calculated, or 48% allowing for the spatial decay.3. The magnitude of the reduction of the electrotonic potential caused by adrenaline was decreased as the concentration of K or Cl ions in the medium was reduced by substituting NaCl or sucrose for KCl or an impermeant anion, benzene sulphonate, for Cl ions. The adrenaline effect remained unaltered when the NaCl was replaced with Tris-Cl.4. It is therefore concluded that adrenaline opens the ion pathways mainly for K and Cl.5. On the basis of the changes in potential and in conductance caused by adrenaline, the equilibrium potential for its action was calculated as - 75 mV.6. The ratio of the Cl component to the K component of the additional conductance increase was obtained as 0.36 using the calculated equilibrium potential and the Nernst potentials for K (-91 mV) and Cl (-31 mV).

Action Potentials↗