Search PubMed⌕ Search

Biomedical subjects

H O Collier

Publications and source records attributed to H O Collier.

At least 73 records · Page 4Linked to original sources
PubMed1974

Biogenic amines and head twitches in mice during ethanol withdrawal.

After chronic administration of ethanol to mice by the intragastric route head twitches occur as part of the ethanol withdrawal syndrome. Treatments which reduce brain 5-hydroxytryptamine or increase brain noradrenaline inhibited ethanol withdrawal head twitches, whereas treatments which increase brain 5-hydroxytryptamine or reduce brain noradrenaline were capable of inducing head twitches in control animals.

5-Hydroxytryptophan↗
PubMed1972

The inhibition by dexamethasone and disodium cromoglycate of anaphylactic bronchoconstriction in the rat.

1. A method for the measurement of anaphylactic bronchoconstriction in the rat is described.2. Dexamethasone inhibited this response in a dose-related manner.3. Disodium cromoglycate antagonized the response. A bell-shaped dose-response curve was obtained with peak activity at 1 mg/kg i.v.4. Meclofenamate was not active when given alone or in combination with dexamethasone.5. Methysergide significantly inhibited the response. Mepyramine, atropine, propranolol and adrenalectomy did not significantly modify the response.6. The relationships of anaphylactic bronchoconstriction in the rat to anaphylactic bronchoconstriction in the guinea-pig and to human asthma are discussed.

Adrenalectomy↗