A young woman with apparent increase in the transverse cardiac diameter.
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Biomedical subjects
Publications and source records attributed to H Ngan.
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To assess the usefulness of endoscopic retrograde cholangiography (ERCP) in the study of acute pancreatitis, 101 of a possible 114 patients (89 per cent) with acute pancreatitis underwent ERCP after recovery from acute illness. In 81 per cent, ERCP was performed within two weeks of recovery. The biliary tract was successfully demonstrated in 87 per cent of the patients and the pancreatic duct in 73 per cent. Roentgenograms of the biliary tract showed stones in the gallbladder in 40 per cent of the patients and in 36 per cent in the biliary ducts. In addition, the gallbladder was not visualized in nine patients. In eight of those patients, the gallbladder was subsequently shown to be abnormal. Other findings of the biliary system included one patient each with clonorchiasis, ascariasis and malignant disease. Changes in the pancreatic duct were detected in 11 per cent of the patients. Most of the changes were consistent with acute or chronic pancreatitis. Minimal morbidity was encountered. ERCP is very accurate in identifying the biliary causes of pancreatitis. In areas where a significant proportion of acute pancreatitis has biliary causes, it should be performed upon all patients soon after resolution of the acute illness to identify those patients who will benefit from early operation upon the biliary tract.
One hundred and ten fine needle aspirations were performed on 73 patients with primary and recurrent gynaecological cancers. The sampling sites included superficial and retroperitoneal lymph nodes, soft tissue masses, liver, lungs, abdominal and pelvic masses, parametrium, thyroid and breast nodules. This relatively simple, safe and yet reliable technique can obviate the need for biopsies in most situations, and a more liberal use of aspiration cytology in gynaecological malignancies is advocated.
We report a case of scrotal dermal chylorrhea associated with chyluria. This is an uncommon complication of chyluria and the only case recorded in our series of 206 patients. Lymphograms showed the presence of abnormal reflux from the inguinal lymphatics into the scrotum.
Postoperative deep vein thrombosis is considered to be rare in Chinese. The 125I-labelled fibrinogen test was used to determine the true incidence of postoperative deep vein thrombosis in Chinese. Deep vein thrombosis was found in 2.6 per cent, a very low incidence compared with Caucasian series.
A series of 32 intracranial arteriovenous malformations in the Chinese is retrospectively studied. Their salient clinical, radiological and morphological features are presented together with their eventual outcome. Contrasting features from reported western series are compared.
Thirty-seven cases of ruptured intracranial aneurysms in the Chinese were retrospectively studied to define their clinical characteristics. The incidence is shown to be low, and a high proportion of anterior communicating artery aneurysms was encountered. Factors contributing to the low incidence are briefly discussed.
A patient with congenital hepatic fibrosis is described in whom portal hypertension with variceal bleeding was the predominant symptom, accompanied by a minor episode of cholangitis Endoscopic retrograde cholangiopancreatography disclosed intrahepatic bile duct strictures, tortuosity, and tubular dilatation, but not cystic dilatation as typical of Caroli's disease, in which cholangitis is known to be the predominant feature. Following the procedure, the patient developed fulminating cholangitis and septicaemia, and died despite surgical decompression of the biliary system.
One hundred and sixty-one cases of chyluria have been studied. The possible aetiological factors, the approach to investigation and the methods and results of treatment have been discussed. In this series, the diagnosis was established by the presence of chyle in the urine. Lymphography was carried out in 90 patients for the localisation of the site of lymphatic reflux while cystoscopic examination after fatty meal was useful in determining the side with the heavier leakage. One hundred and nineteen cases responded to conservative treatment and only 42 cases required operative treatment. Stripping of the renal pedicle via the retroperitoneal route gave the best results.
Lymphograms of 1,000 patients were reviewed with special reference to the occurrence of hepatic oil embolism following the procedure. Oily contrast medium ("Lipiodol" ultra-fluid) was found in the liver in seven cases, five of whom had carcinoma of the cervix uteri. Hepatic oil embolism was not encountered in patients with lymphomas in this series. Complete or partial lymphatic obstruction was present in all seven cases and one patient had almost complete obstruction of the inferior vena cava. Malignant disease need not always be the predisposing factor since hepatic oil embolism occurred in one patient with retroperitoneal fibrosis. The routes through which the contrast medium may reach the liver are discussed and lymphaticoportal communications in the mesentery are thought to play an important role. Contrast was invariably seen in the liver within two hours of commencement of the injection and was still faintly visible in one case three and a half months later. The way in which the contrast-pattern in the liver changes with time is described. An attempt is made to correlate the radiological appearances with the fate of the contrast medium in the liver.
Endoscopic retrograde cholangiograms were studied in 52 patients with recurrent pyogenic cholangitis, a condition which is prevalent in Asia and in which there is a primary bacterial cholangitis. The earlier changes of recurrent pyogenic cholangitis were identified and found to be confined to the intrahepatic biliary tree. The left hepatic duct was more severely affected than the right hepatic duct and had a higher infestation by clonorchis. The severity of radiological changes correlated well with the duration of illness and the need for surgery. Gallstones were present in 34.2% of the patients and pancreatic ductal abnormality in 7.7%. The decision for surgery could be made early and accurately, and the type of surgery and the assignment of surgeons could be planned in advance--situations which conventional intravenous cholangiograms could not achieve. Cholangitis complicated endoscopic retrograde cholangiograms in 23.1% of the initial 26 patients without antibiotic cover but none of the subsequent 26 in whom this was used.
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Ninety patients with chyluria were studied by bilateral pedal lymphography. The retroperitoneal lymphatic vessels were dilated, tortuous and increased in number in 61% of cases while the appearance of the lymph nodes was abnormal in 67% of cases. Renal lymphatic reflux, either bilateral or unilateral, was seen in 93% of patients. A correlation (P greater than 0.007) was observed between the site of origin of the cisterna chyli and side of unilateral renal lymphatic reflux. There was no evidence of thoracic duct obstruction although the thoracic duct was more than 3 mm in calibre in seven cases. Lymphography was also performed on 22 patients who had undergone stripping of the lymphatics along the renal pedicle to determine if surgical disconnection was complete. The pathogenesis of chyluria is briefly discussed.
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Eight cases of non-Hodgkin's lymphoma presenting with bone symptoms are reported. The radiological appearances of these tumours are described. The importance of radiology in differentiating a primary lymphoma of bone from a lymphoma arising from other organs which has subsequently metastasised to the skeleton is briefly discussed.
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