Search PubMed⌕ Search

Biomedical subjects

H Murphy

Publications and source records attributed to H Murphy.

49 records · Page 3Linked to original sources

Double blind trial of ritodrine and placebo in twin pregnancy.

In a double blind trial, 25 patients with twin pregnancy were given 40 mg of ritodrine hydrochloride by mouth daily and 24 similar patients received a placebo. The ritodrine group had no significant prolongation of pregnancy nor increase in birth weight, and a high incidence of side effects occurred.

Clinical Trials as Topic↗

Plaque assay of avian sarcoma viruses using casein.

The caseinolytic activity of several strains of Rous sarcoma virus (RSV), conditional and nonconditional mutants of RSV, and nontransforming avian leukosis viruses was investigated. Only those viruses capable of transforming chick fibroblasts in vitro induced lysis of casein incorporated into an agar overlay. Lysis produced distinct clear areas in the turbid casein-agar gel which allowed a quantitative "plaque" assay of cell transformation. Casein plaque formation could not be separated from morphological conversion in cultures infected by wild-type RSV strains. In plates infected by mutants temperature sensitive for transformation, the caseinolytic activity appeared to be affected by temperature to a lesser extent than morphological conversion.

Avian Leukosis Virus↗

Diabetes in childhood.

Insulin-dependent diabetes mellitus is the most common endocrine disorder of childhood. Early diagnosis is important. A multidisciplinary team approach enables families to assume responsibility for self-management. The paediatric diabetes nurse specialist is a key member of the team.

Child, Preschool↗