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Biomedical subjects

H Murakami

Publications and source records attributed to H Murakami.

At least 811 records · Page 45Linked to original sources
PubMed1976

Case report: a bleeding Meckel's diverticulum diagnosed by selective arteriography.

The diagnosis of a bleeding Meckel's diverticulum was made by angiography in a 71 year old man who presented with melena and hemorrhagic shock. Emergent angiographic examination revealed an extravasation of contrast media from the ileal artery, which suggested a bleeding from the Meckel's diverticulum. The case illustrates the utility of selective angiography in case of gastrointestinal hemorrhage, where the lesion is beyond the range endoscopy.

Aged↗
PubMed1975

Studies on caerulein (FI6934). Absorption, distribution, metabolism and excretion of caerulein.

35S-Caerulein (35S-FI6934) was administered intramuscularly into rats (280 mug/kg), rabbits (380 mug/kg) and mice (3.3 mg/kg). Blood level of radioactivity in rats and rabbits reached the maximum at 5 and 15 min after administration, respectively, and then decreased rapidly. In both rats and rabbits, the radioactivities were excreted mainly into the urine. The physiological activity of FI6934 was detected in the blood of rats and rabbits collected within 15 and 30 min after injection respectively, and in the bile of rats collected within the first 2 hr. In rats, the radioactivities were densely distributed in kidney, liver, pancreas, and intestine. Four metabolites of 35S-FI6934 were isolated by paper chromatography from rat urine (i.m., 500 mug/kg). The main metabolites, F-I and F-II, were negative to nynhydrin and to the Ehrlich reagent and carried no physiological activity. 35S-Chym-I, which was prepared by digesting 35S-FI6934 with chymotrypsin, was injected to rats (i.m. 16 or 8 mg/kg/. The metabolite, C-I, isolated from the urine was considered to have a very similar structure to F-I from the results of paper chromatography and paper electrophoresis. By amino acid analysis, the structure of C-I was estimated to be as follows: Pyr-Gln (or Glu)-Asp-Tyr-Thr-Gly. (see article).

Amino Acids↗
PubMed1975

A digital auto-recorder for measuring the drinking frequency of mice.

An inexpensive, automatic digital recorder to measure the drinking frequency of mice was designed. When an animal licked the spout of the water bottle, it closed the path of the current of the amplifier input circuit and a module converted the closure signal into an electric pulse. A camera preset by a timer automatically photographed the counter which had accepted the pulse. The apparatus was inexpensive and estimated the drinking frequency of many mice individually and simultaneously. This system is applicable as a pulse-recorder to physical phenomena other than water intake.

Animals↗