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Biomedical subjects

H Morinaga

Publications and source records attributed to H Morinaga.

49 records · Page 3Linked to original sources
PubMed1982

Left ventricular hypertrophy in non-rheumatic myocarditis in children.

Fifty-three Japanese children with non-rheumatic myocarditis were investigated with regard to left ventricular hypertrophy (LVH), which was assessed electrocardiographically. Follow-up periods ranged from 12 to 58 months with a mean of 22.8 months. Left ventricular posterior wall thickness (LVPWT) evaluated echocardiographically was compared to the electrocardiographic findings of LVH. The overall prevalence of LVH was 30.2% (16 patients). In 3 patients, LVH was detected during the first examination. In the other patients, however, LVH was detected later during the follow-up periods. In all but 2 patients, LVH disappeared during the follow-up periods. The development into hypertrophic cardiomyopathy was evident in only one patient. The LVPWT showed no definite relation to the presence of LVH. Thus, LVH on an electrocardiogram appears to be a common finding in children with non-rheumatic myocarditis.

Cardiomegaly↗
PubMed1982

New plastic joints for plastic orthoses.

Plastic joints for orthoses have more advantages than metal joints. They are lightweight, noiseless comfortable to use, rust proof, corrosion free, and radiolucent. Two types of plastic joints were developed by the authors, one for the ankle joint and the other for the knee joint, elbow joint or hip joint. Polypropylene was chosen as the joint material because of its appropriate flexibility and toughness.

Ankle Joint↗
PubMed1981

Clinical appraisal of the antideoxyribonuclease-B (ADNB) by means of streptonase-B test (Wampole).

Titers of antideoxyribonuclease-B (ADNB, by Streptonase-B test), antistreptolysin-O (ASO, by Rantz-Randall's micromethod) and Kinase test (antivaridase agglutination test) were performed on 118 sera of patients with suspected streptococcal infection and compared. Between ASO and ADNB, a fairly significant correlation was seen (r = 0.69), but many cases in which ADNB exceeded ASO were observed. Between Kinase and ADNB, no significant correlation was seen (r = 0.49). Successive determination of antibody titers were made in 14 consecutive patients with acute glomerulonephritis, anaphylactoid purpura nephritis, rheumatic fever and chronic rheumatic heart disease. In general, ADNB titer was significantly higher than ASO with few exceptions. The duration of high titer of ADNB was much longer than ASO Kinase titers were sometimes unstable. Throughout this study it has been noted that the result of ADNB was very easily to read and was highly reproducible. There were no nonspecific or pseudopositive reactions. Therefore, ADNB is useful for the diagnosis of streptococcal infection and its complication especially when other antibody titers give negative or doubtful results.

Adolescent↗
PubMed1980

Sequelae of nonrheumatic myocarditis in children: a follow-up study.

A follow-up study of childhood myocarditis for at least 12 months (12--39 months, average 19.7 months) was made on 26 patients. Regular cardiological examinations (X-ray, ECG, PCG, MCG and UCG) and serum enzyme studies (especially LDH isozyme and CPK isozyme) were done. Clinical and cardiological normalization was seen in 13 (50.0%), not necessarily with normalized enzyme study. Major residual abnormalities were: CRBBB (3), VPC (3), abnormal Q (1), A-V block I (1), large IVth sound (1) and chronic nonobstructive cardiomyopathy (HNCM) (1). Mild, transient recurrences were seen in 3. Enzyme abnormalities, which existed at the first visit in all cases, disappeared only in 12. This suggests that somewhat active inflammatory process may persist for years, even after clinical and cardiological normalization. The patient with HNCM had a heavy familial history of cardiomyopathy. The relationship between myocarditis and cardiomyopathy was discussed. It is necessary to examine every patients with cardiomyopathy from the stand of view of myocarditis.

Adolescent↗
PubMed1979

Clinical aspects of nonrheumatic myocarditis in children.

Sixty-eight patients of clinically diagnosed myocarditis, 0--15 years of age, were followed up and analyzed. Forty (58.8%) were males. The majority were older than 5 years. Clinical courses were rather mild, chronic and self-limiting at large. Only 1 case had a relation to chronic cariomyopathy. Exertional symptoms (chest pain, chest distress, syncope) were seen in 25 (36.8%). ECG changes were very common: the majority were nonspecific ST elevation, depression or both, mainly in leads II, III, V5 and V6. Positive Master' test, prolonged QTc, widened mean spatial QRS-T angle and various arrhythmias were also observed. Cardiac performance, estimated by echocardiogram and phono-mechanocardiogram was lowered in 41 (60.3%). Large IV sound and large A wave in apexcardiogram were also frequently found. All but 3 patients showed continuous elevation of serum enzymes, namely, LDH, LDH-1/LDH-2, CPK, CPK-MB, HBD and GOT. Etiological evidences were obtained by serological study in 11 cases (16.2%): 2 of Coxsackie B-1, 3 of Coxsackie B-2, 1 of Coxsackie B-4, 2 of mycoplasma pneumoniae, 1 of cytomegalovirus, 1 of ECHO-7 and 1 of rubella. We proposed a criteria for diagnosis of myocarditis as follows: (1) Exertional symptoms. (2) ECG findings. (3) Serum enzyme abnormality. (4) Lowered cardiac performance. (5) Cardiomegaly. (6) Changing character of all signs and symptoms.

Adolescent↗