[Ubiquinones and related compounds. XXIV. Syntheses of quinones in the presence of metals].
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Biomedical subjects
Publications and source records attributed to H Morimoto.
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An active, cell-free protein synthesizing system has been obtained from yeast mitochondria. The system is stimulated by both polyuridylate and R17 RNA and is sensitive to inhibitors of bacterial protein synthesizing systems. A comparison is made between this system and that found in the cytoplasm of yeast.
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A method for the preparation of mitochondrial ribosomes from yeast is presented. Mitochondrial ribosomes differ from their cytoplasmic counterpart in nucleotide composition, electrophoretic mobility of a number of their respective ribosomal proteins, and thermal denaturation profiles. The mitochondrial and cytoplasmic ribosomes have identical sedimentation coefficients (80 S) and dissociate into 60S and 40S subunits. These findings demonstrate that, in yeast, mitochondrial ribosomes are distinct from cytoplasmic ribosomes.
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