Effects of long term exposure to trichloroethylene on learning behaviour in rats.
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Biomedical subjects
Publications and source records attributed to H Miyake.
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The local anti-inflammatory effects of a synthetic corticosteroid, 17 alpha, 21-diacetory-2-bromo-6 beta, 9 alpha-difluoro-11 beta-hydroxy-1,4,-pregnadiene-3,20-dione (F-2), were evaluated by granuloma and granuloma pouch method. F-2 had an intensive and probably persistent topical anti-inflammatory activity. The systemic effects of F-2 were evaluated by measuring the thymus and adrenal gland weight. F-2 did not induce significant systemic effects at as high a dose as 125 times the effective dose.
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When performing a microvascular anastomosis, some surgeons use a splint and others do not. We compared the difference in intravascular reactions observed in the carotid artery of the rat anastomosed with these two techniques by observation with a scanning electron microscope. Thrombus formation was more prominent in the artery anastomosed using a splint. The difference was most remarkable 20 minutes after anastomosis. With time, the difference became less remarkable and was no longer present by seven days. By fourteen days, the anastomotic site was covered with neoendothelium. It is concluded that there is little difference in the final outcome achieved by the two methods.
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In taking a X-ray photography of the head in sagittal projection, it is most important that the center of the X-ray beam passes exactly through the median-sagittal line. If the subject turns his head either to the right or to the left, the paranasal sinuses become denser on one side, leading to erroneous interpretation of the radiographic findings. In order to eliminate such a misinterpretations, studies were carried out on the following: 1) Application of a standard of what degree of head turning to either side would start to influence judgment of the shadow of the paranasal sinuses. 2. Application of a standard to judge whether they are projected to an exact center position or not in actually diagnosing the X-ray films.
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When chlorella was treated with alkali after decolorization by methyl alcohol and then fractionated by gel filtration, the fraction showed a depressive effect. The blood pressure of SHRSP and SHR showed a fall of an average of 63 mmHG 1 hour after intravenous administration, 47 MMHg 2 hours after intraperitoneal administration. The blood pressure of normotensive Wistar rats also showed a fall of an average of 32 mmHg 1 hour after intravenous administration.
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