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Biomedical subjects

H Milon

Publications and source records attributed to H Milon.

157 records · Page 9Linked to original sources
PubMedDate not supplied

Computer-assisted patient-care management.

A computer-assisted patient-care management system is currently operating in two patient-care units as part of a pilot project at the Hôpital Cardiologique, a member institution of the Hospices Civils de Lyon. The system includes the management of administrative records (notice of admission set to the patient-care unit, appointment for admission sent to the patient, notice of admission set to the physician requesting hospitalization, admissions and discharges, patient census) and of patient-care records (orders, examinations, laboratory tests, medications, injections and treatments, a summary list or orders to be carried out during the day, labels for laboratory specimens and requistions for the tests and examinations to be performed); and the medical management of the patient (clinical summary of patient status at admission, results of tests and examinations, summary of hospitalization, data for research and statistics). Computerization was begun in 1977, following the implementation of individualized patient-care records in 1976. The system will be evaluated in 1978 and extended to the remainder of the hospital (18 patient-care units) by the end of 1979.

Computers↗
PubMedDate not supplied

[Estimation of the frequency of reno-vascular hypertension among unselected hypertensives (author's transl)].

In practical terms the frequency of renovascular hypertension can only be measured from groups of hospitalized hypertensives, in which severe forms and young subjects are over-represented, thus leading probably to an overestimate. Using a group of 1 009 consecutively hospitalized hypertensives, the frequency of renovascular hypertension was measured in 18 subgroups defined by sex, age (three classes) and blood pressure (three classes). For each subgroup the specific rate was then multiplied by the prevalence of the corresponding category in the population of unselected 20-64 years old hypertensives. This method led to the following conclusions: about 2% of the unselected hypertensives would be candidates for surgical correction of renovascular hypertension and 0.5% would be cured.

Adolescent↗
PubMedDate not supplied

[Markers of cardiovascular remodeling in hypertension].

UNLABELLED: Our goal was to study the relative influence of systolic blood pressure (SBP) and plasmatic markers of sympathetic and renin-aldosterone systems (RAS) activities to left atrial diameter (LAD), left ventricular posterior wall thickness (LVPWT) and pulse wave velocity (PWV), which reflect cardiovascular remodeling in hypertension. METHODS: In 227 consecutive patients with hypertension (mean age +/- SD: 53.3 years +/- 13.4, 126 men), we measured: PWV, LAD, LVPWT, mean 24-hours SBP, plasma renin activity, and plasma aldosterone and catecholamine levels. Multiples linear regression analyses were performed to test statistical associations between hemodynamic and neurohumoral factors, and cardiovascular remodeling parameters, after adjustment for age, gender and body mass index. RESULTS: LVPWT was positively correlated to SBP as well as to plasma aldosterone and meta-noradrenaline (p < 0.001). LAD and PWV were related to SBP but not to any of the biological variables. Moreover, LAD correlated to PWV independently of SBP (p < 0.05), whereas after SBP inclusion in the model, there was not significant correlation between LAD and LVPWT nor between LVPWT and PWV. CONCLUSION: In hypertension, the development of cardiac hypertrophy depends on SBP and the sympathetic and renin-aldosterone systems activities. The RAS is not involved in the PWV nor LAD modifications. Strong association between LAD and PWV suggest that left atrial enlargement, that may be considered as a marker of diastolic function, may results more from arterial stiffness than from ventricular hypertrophy.

Adult↗
PubMedDate not supplied

[Comparison of antihypertensive and metabolic effects of lisinopril 20 mg/hydrochlorothiazide 12.5 mg fixed combination and captopril 50 mg/hydrochlorothiazide 25 mg fixed combination].

The antihypertensive and metabolic effects of lisinopril 20 mg/hydrochlorothiazide 12.5 mg in fixed combination were compared with those of captopril 50 mg/hydrochlorothiazide 25 mg in fixed combination in a double-blind clinical trial. After a 3-week placebo run-in period, two parallel groups of hypertensive patients (188 patients in total) each received one treatment once a day for 6 weeks. Blood pressure was measured with a mercury sphygmomanometer and on two occasions by 24 h ambulatory blood pressure monitoring (ABPM). Results indicate that both treatments have similar effects on casual blood pressure measurements, while ABPM recordings show that the lisinopril 20 mg/hydrochlorothiazide 12.5 mg combination is more effective during the last period of the dosing interval. Lisinopril 20 mg/hydrochlorothiazide 12.5 mg as combination antihypertensive treatment does not induce alterations in serum potassium and triglycerides.

Adult↗