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Biomedical subjects

H Michael Dreher

Publications and source records attributed to H Michael Dreher.

6 recordsLinked to original sources
PubMed2003

The effect of caffeine reduction on sleep quality and well-being in persons with HIV.

OBJECTIVES: With reports of high rates of sleep disruption in Human Immunodeficiency Virus (HIV) + persons, this study tested whether there were differences in sleep quality and well-being between a group of HIV+ persons who reduced their caffeine intake from baseline by 90% or greater for 30 days (n=44) versus a group of HIV+ persons who continued their usual caffeine consumption (n=44). METHODS: Subjects were administered pre- and post-Pittsburgh Sleep Quality Index (PSQI), Perceived Well-being Scale-Revised (PWB-R) and MOS-HIV Health Survey instruments, with MOS-HIV summary scores used as a covariate. RESULTS: On ANCOVA analysis for sleep quality (F=14.032, P<.001), a 35% improvement in sleep among experimental subjects was identified. There was no significant difference between the two groups on ANCOVA analysis for well-being (F=0.111. P=.739). CONCLUSIONS: High levels of caffeine consumption may have an exacerbating effect on already prevalent HIV-related sleep pattern disturbances, and significant reductions of caffeine may improve sleep quality.

Adult↗
PubMed2002

Narcolepsy.

Narcolepsy is a chronic disorder of EDS. All patients experience EDS. Other symptoms include cataplexy, sleep paralysis, hypnagogic hallucinations, and disrupted nocturnal sleep. Treatment, usually with stimulants and low-doses of antidepressant medications, can dramatically improve the patient's quality of life. Although only advanced practice nurses may be actively involved in the diagnosis and treatment of this disorder, all nurses can encourage their patients who complain of EDS to consult a specialist in sleep disorders medicine, provide emotional support after diagnosis, and educate patients and their families about narcolepsy and its treatment.

Behavior Therapy↗
PubMed2002

A new transcontinental disease: the West Nile virus.

The West Nile Virus caught New Yorkers by surprise in the summer of 1999. The prompt reporting of cases, as well as swift responses from local and state health departments and the Centers for Disease Control and Prevention, can prevent larger outbreaks of the virus.

Animals↗
PubMedDate not supplied

Management of pharmacologically induced neuromuscular blockade using peripheral nerve stimulation.

Currently, many critically ill patients are treated with neuromuscular blocking agents to facilitate endotracheal intubation, mechanical ventilation, and manage confused, combative, head injured, and status epileptus patients. To prevent persistent pharmacologically induced paralysis, the aide of a peripheral nerve stimulator and clinical indicators may help determine the minimal effective drug dose to facilitate safe neuromuscular blockade. The purpose of this article is to provide nursing clinicians the essential knowledge to manage patients with neuromuscular blockade effectively using peripheral nerve stimulation monitoring.

Drug Monitoring↗
PubMedDate not supplied

Measuring health status in HIV disease: challenges from a sleep study.

This article reports on the challenges of measuring health status in a study that tested whether there were differences in sleep and well-being between a group of persons with HIV who reduced their caffeine intake from baseline by 90% or greater for 30 days (n = 44) versus a group of persons with HIV who continued their usual caffeine consumption (n = 44). The MOS-HIV Health Survey summary scores were used as health status measures and as covariates. While results indicated that physical and mental health status improved among experimental group subjects, several methodological considerations are offered for further HIV/AIDS researchers: (1) How should health status with various degrees of disease progression be classified? (2) How can health status from different CD4 and HIV viral load measurements be properly inferred? (3) If opting to also employ a health status questionnaire, should general or disease-specific instruments be used?

Adult↗