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Biomedical subjects

H Mellerowicz

Publications and source records attributed to H Mellerowicz.

At least 37 records · Page 2Linked to original sources

[Ergometric investigations of the tension-time-index and of the PWC 170 in patients with borderline and stable hypertension in comparison with normals (author's transl)].

1. Comparative measurements of the Tension-Time-Index during ergometric work and of the Physical Working Capacity 170 were carried out in patients with borderline (n = 24) and stable hypertension (n = 51) in comparison with normals (n = 47), aged 20-60 years. 2. The Tension-Time-Index which is generally accepted as an indirect estimation of the myocardial oxygen consumption was significantly (p < 0.001) higher in the borderline hypertensives (30.5%) and in the hypertensives (41.7%) already at the low work load of 50 watt. 3. The PWC170 which has been shown to be a reliable ergometric method for determination of the physical performance was 21.2% lower (p < 0.001) in the hypertensives with 2.71 +/- 0.74 W/kg body weight in comparison with 3.44 +/- 0.8 W/kg body weight of the normals. Already the borderline hypertensives had a reduced PWC170 of 2.93 +/- 0.7 W/kg body weight. 4. Therefore hypertensives should perform a dosed endurance training of middle intensity, which results in a reduction of heart rate, systolic blood pressure and consequently of the Tension-Time-Index and which improves the Physical Working Capacity. These favourable effects of training are of great benefit especially for those patients also suffering from ischemic heart disease because the myocardial oxygen consumption is the limiting factor of physical performance. 5. In order to prevent acute and chronic vascular complications caused by excessive blood pressure increases during physical activity in hypertensives, ergometric tests for dosage of training and if necessary an antihypertensive treatment should be applied before starting the training program.

Adult↗

[Experimental experience with autologous nerve-transplantation in rabbits (author's transl)].

Autologous nerve transplantations of the tibial nerve were carried out in 15 rabbits. In an average period of 19 weeks a return of function could be observed in 13 of the animals. Neuro-physiological, histological and scanning-electron microscopic examinations were done. A comparison was performed with results after simple nerve suture, done under equal circumstances. Nerve suture leads to a relative better regeneration. To explain this result the formation of a scar in the distal suture was discussed.

Animals↗

[Comparative measurements of PWC170 with work steps of different load increase and duration (author's transl)].

The "Physical Working Capacity" (PWC170) which has been shown to be an ergometric method for determination of the physical performance is due to measurement of heart rate during physical work under steady-state conditions. However the practical application of those methods of multiple work steps of six minutes is limited due to the time-consuming procedure. Therefore, we measured in 30 test-persons PWX170 with work-steps of 50 Watt/6 min. in comparison with 25 Watt/2 min. The difference between these two test-series of 3.7% was not significant. For daily determination of PWC170 the more time-saving procedure with work steps of 25 Watt/2 min. is suggested.

Adolescent↗

[The speed of nerve-conduction after micro-surgical suture of the tibial nerve of the rabbit (author's transl)].

Isolated division of the tibial nerve in the thigh preserving the peroneal and sural nerves does not cause loss of normal position of the animal, in particular of sitting. Nor does it lead to pressure sores. The animals are fitter then after division of the sciatic nerve. Microsurgical suture of the isolated tibial nerve in the thigh of the rabbit with 1 or 2 simple sutures with 10 x 0 thread show that an average recovery can be achieved in over 80 per cent. As few sutures as possible should be used. Otherwise there with be scarring and no return of function.

Action Potentials↗

[Ergometry].

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Blood Pressure↗