[Present knowledge on the pathogenesis of common psoriasis as the basis for a scientifically founded therapy. I. Pathogenesis of common psoriasis].
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Cell Differentiation↗
Biomedical subjects
H Meffert
Publications and source records attributed to H Meffert.
[Acceleration of the ultra-violet provoked lipid peroxidation of human surface fat by means of anti-psoriatic substances].
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Adipose Tissue↗
[Acceleration of UV-induced lipid peroxidation by antipsoriatics].
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Acceleration↗
[The effect of lipoperoxide and dithranol (cignolin) on psoriasis vulgaris].
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Anthracenes↗
[Modification of lipoperoxides of the human skin surface by ultraviolet rays in vitro and in vivo].
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Humans↗
[Measurement of skin temperature with the infra-red radiation measuring device by Kortum].
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Humans↗
[Cholesterol and cholesterol ester in the surface lipid of psoriasis patients].
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Cholesterol↗
[Thin-layer chromatographic deterimation of cholesterol and cholestrol esters in the serum of psoriasis vulgaris patients].
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Cholesterol↗
[Comparative studies of senstive chronaxy in various forms of scleroderma and lichen sclerosus et atrophicus].
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Chronaxy↗
Determination of the horny layer profile by tape stripping in combination with optical spectroscopy in the visible range as a prerequisite to quantify percutaneous absorption.
A new method was developed to determine the horny layer profile of volunteers using tape stripping in combination with UV/visible spectroscopy. The optical absorbance and the weight of corneocyte aggregates were compared as parameters for the determination of the mass of the horny layer particles fixed to the individual tapes. It was shown that the potential disturbances influencing both parameters must be considered critically before calculating the correlation factor, found as R2mean = 0.93 +/- 0.05. It was proven that the absorbance in the visible range is better suited than the weight to quantify the amount of corneocyte aggregates removed by a single strip. The new method allows an exact anatomical localization of the individual tapes and all data obtained within the depth profile of the stratum corneum. This was exemplified by the determination of the penetration of chemical and physical UV filters into the horny layer.
Adult↗