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Biomedical subjects

H Mawhinney

Publications and source records attributed to H Mawhinney.

33 records · Page 2Linked to original sources
PubMed1975

The immunoglobulin class responses to oral poliovaccine in coeliac disease.

An indirect immunofluorescent technique has been used to study the incidence and immunoglobulin class distribution of the serum antibody response to type II oral poliovaccine in patients with adult coeliac disease and matched control subjects. Nineteen out of thirty-eight (50%) patients with coeliac disease showed an antibody response compared with only seven out of thirty-eight (18%) control subjects. Poliovirus-specific IgA responses were observed in sixteen out of thirty-eight (42%) coeliac patients compared with seven out of thirty-eight (18%) control subjects, while poliovirus-specific IgG responses were observed in only ten out of thirty-eight (26%) coeliac patients and four out of thirty-eight (11%) control subjects. No poliovirus-specific IgM responses were observed. The pre-immunization poliovirus-specific IgA titres of those subjects who showed an antibody response were significantly higher in the coeliac group than in the control group.

Adolescent↗
PubMed1975

Anti-reticulin antibody in jejunal juice in coeliac disease.

Anti-reticulin antibody has been demonstrated in the jejunal juice of eight out of fourteen (57%) untreated coeliac patients, one out of twelve (8%) patients with normal jejunal biopsies and none of ten normal control subjects. The jejunal juice antibody was invariably of the IgA class. It is suggested that the presence of anti-reticulin antibody in the jejunal juice in coeliac disease supports the hypothesis that this antibody is secreted in response to reticulin antigens present in the diet.

Adolescent↗
PubMed1975

HL-A3 and HL-A7 in pernicious anaemia and autoimmune atrophic gastritis.

Increased frequencies of HL-A7 and the HL-A3,7 haplotype have been demonstrated in pernicious anaemia. There was no significant increase in any HL-A specificity in autoimmune atrophic gastritis. In the whole series of patients with either pernicious anaemia or atrophic gastritis there was a significant increase in the frequency of HL-A3. No association has been found between any HL-A specificity and an increased incidence of either serum gastric parietal cell or intrinsic factor antibody compared with the overall incidence in pernicious anaemia, atrophic gastritis or in the whole series.

Anemia, Pernicious↗
PubMedDate not supplied

The computer in the consulting room. What can it do for the physician?

Helen Mawhinney, M.D., of McLure, Moynihan and Associates and the University of California-Los Angeles, and Brad Dodge of Health Communication Services Inc., write about the use of computer-based medical records and their effects on patient care, decision making and data generation.

Cost-Benefit Analysis↗