Search PubMed⌕ Search

Biomedical subjects

H Matsui

Publications and source records attributed to H Matsui.

At least 865 records · Page 48Linked to original sources
PubMed1968

Tritiated digoxin binding to (Na+ + K+)-activated adenosine triphosphatase: possible allosteric site.

Tritiated H(3)-digoxin specifically binds to a cardiac (Na(+) + K(+))-activated adenosine triphosphatase. In the presence of adenosine triphosphate and other nucleoside di- and triphosphates, binding is stimulated by sodium ion, the apparent rate constant being similar to that reported for phosphorus-32 incorporation from adenosine triphosphate and for the adenosine triphosphatase activity. In the presence of magnesium, manganese, inorganic phosphate, or other ions, sodium ion inhibits binding. The data support an allosteric type of sodium-potassium ion pump.

Adenosine Triphosphatases↗
PubMedDate not supplied

Attachment and invasion of high- and low-metastatic clones of RCT sarcoma in a three-dimensional culture system.

High- and low-metastatic clones established from poorly differentiated murine sarcoma (RCT sarcoma) spontaneously developed in C3H/He mice were used in this study. Attachment and invasion, which are factors likely related to metastatic ability, of these clones were investigated in a three-dimensional culture system using embryonic chick heart fragments and tumor cell aggregates. The effects of Nocodazole, which interferes with the function of microtubules, and cytochalasin B, which affects the actin assembly in cytoplasmic extensions, on these factors were also examined. Metastatic ability was correlated with attachment and invasiveness of RCT sarcoma. Invasiveness of tumor cells was suppressed by the addition of Nocodazole to the culture medium. Since the disappearance of cell polarity, resulting from the inhibition of tubulin assembly, was found to coincide with the suppression of invasion, directional migration is considered to be involved in the invasion of tumor cells. Cytochalasin B caused a marked decrease in the ratio of attachment of tumor aggregates to embryonic chick heart fragments. The increased ability of invasion and attachment of RCT(+) cells compared with RCT(-) cells seems to contribute to their propensity to metastasize.

Animals↗
PubMedDate not supplied

Complications of percutaneous transluminal coronary rotational ablation in Kawasaki disease.

A 13-year-old boy who suffered from Kawasaki disease at the age of 2 months underwent percutaneous transluminal coronary rotational ablation for coronary stenosis. After this procedure, coronary spasm occurred and he experienced acute myocardial infarction within 10 days. Total occlusion of the LAD was demonstrated by coronary angiography. Coronary spasm after such a procedure is one of the most dangerous complications causing acute myocardial infarction.

Atherectomy, Coronary↗