[A case of peripheral facial paralysis in Horton's disease].
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Aged↗
Biomedical subjects
H Massiou
Publications and source records attributed to H Massiou.
[Recent data on Schwann cells].
Because of the role they play in the physiopathology of peripheral neuropathies, Schwann cells have been the subject of numerous studies for some ten years. Schwann cells originate in the ectoderm. They migrate along the myelinated and the unmyelinated axons of peripheral nerves, and lie on a basal lamina. They are responsible for the myelination of peripheral nerves; whether the Schwann cell does or does not form a myelin sheath is determined by the type of axon with which it associates. Recent techniques, such as chimaeric quail-chick embryos, biochemical analysis of human peripheral nerve biopsies, Schwann-cell cultures, nerve grafts, mouse mutants, have permitted some progress. The biochemical composition of peripheral myelin is almost completely known. In vitro, Schwann cells can synthesize myelin-specific molecules. Interactions between axons, Schwann-cells and extra-cellular space have been observed.
Animals↗
Recurrent alternating ophthalmoplegia with iridoplegia in a young diabetic.
Regressive painless left third nerve paralysis with pupillary involvement was followed 6 months later by a right painful complete ophthalmoplegia. The two attacks resolved without treatment. The patient, 22 years old, was recognized diabetic and no other cause was found. It is suggested that this clinical pattern is characteristic of the involvement of two different territories of third nerve vascularization.
Adult↗
[Motor neglect of thalamic origin: report on two cases (author's transl)].
Two cases of thalamic lesions with motor neglect are presented. The syndrome of motor neglect was complete in those cases with a) underutilization of left limbs, but good utilization upon verbal orders, b) loss of placement reaction, c) weakness of movement when hand was approaching the target, d) weakness of motor reaction to nociceptive stimuli. Those cases confirm that motor neglect exists after thalamic lesions and bring pathologic clues for topographic discussion. Motor neglect seems to be a particular case of partial unilateral neglect throwing some doubt on the hypothesis of a global trouble of hemispheric activation. Prevalence of left motor neglects suggests some linkage between propositional motility and language. One may suppose that in the right hemisphere language is able to have a vicarious action when spontaneous activation is lost; at the opposite, in the left hemisphere language and motility would be too linked to let this dissociation be generally possible.
Brain Neoplasms↗
[Quality of life and migraine. Validation of the QVM questionnaire in hospital consultation and in general medicine].
The feasibility, the validity and reliability of the questionnaire "Qualité de Vie et Migraine" (QVM) were assessed during a study performed on 107 patients recruited either in neurological departments in hospitals (N = 58) or by G.P. (N = 49). The study was designed as a Test-Retest, the self-questionnaire being filled twice at an interval of one week. The filling-in time was an average 7 min in hospital and 11 min for G.P.'s patients. The missing values were quite rare, between 1% and 2%. The items were assessed "very interesting" or "interesting" by 94% of the patients, and "easy" or "fairly easy to understand" by 96%. The principal component analysis performed on the whole sample allowed the extraction of 4 meaningful factors which were in agreement with the pre-defined structure of the questionnaire QVM. The 1st axis was a factor of psychological repercussion, the 2nd axis was a factor of functional and somatic repercussion, the 3rd axis was a factor of social repercussion and the 4th one was a factor of disturbance generated by the treatment. The QVM questionnaire allowed the calculation of a global index of quality of life and indexes according to the multifactorial structure. The global index was significantly higher for the most severe patients recruited in hospital, which means that the repercussion of migraine on quality of life was greater than for G.P.'s patients.(ABSTRACT TRUNCATED AT 250 WORDS)
Adolescent↗