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Biomedical subjects

H Magometschnigg

Publications and source records attributed to H Magometschnigg.

32 records · Page 2Linked to original sources
PubMed1992

Prospective clinical study with in vitro endothelial cell lining of expanded polytetrafluoroethylene grafts in crural repeat reconstruction.

A nonrandomized prospective clinical study was undertaken to evaluate the technique and efficacy of in vitro endothelial cell lining of synthetic grafts. Twenty-six patients (10 men and 16 women with a mean age of 68.4 years; range, 49 to 80 years) with end stage chronic peripheral vascular disease requiring reoperation were entered into the study. In 13 patients venous endothelial cells were harvested 4 to 7 weeks before operation, grown to confluency in culture flasks, and seeded onto the inner surface of expanded polytetrafluoroethylene grafts. Thirteen patients received untreated expanded polytetrafluoroethylene grafts and served as a control. A scoring system with use of intraarterial angiography was used to assess disease severity. No statistically significant differences in angiographic score were seen between the two groups, indicating comparable severity of disease. Early secondary graft patency (0 to 30 days) was 92% for the in vitro endothelial cell lining group and 53% for control patients. The amputation rate after 18 months for the in vitro endothelial cell lining group was 15%, with a 31% rate in the control group. The functional performance of the in vitro endothelial cell lining bypasses was superior to that of untreated bypass grafts during the observed follow-up period. These early results suggest that in vitro endothelial cell lining is a method that can reduce the early occlusion rate now seen after repeat reconstruction of crural vessels.

Aged↗
PubMed1991

[Percutaneous transluminal implantation of the Günther cava filter: experience based on 22 patients].

During the last three years, Günther cava filters were implanted in 20/22 patients. The indications for the procedure were single pulmonary emboli in 4, recurrent pulmonary emboli in 6 and pelvic vein thromboses with free thrombus but without pulmonary emboli in 12. In 2 patients implantation of the cava filter could not be carried out because of low position of the renal veins. 15 patients were re-examined 2 weeks to 20 months after the introduction of the filter. In no cases was there clinical evidence of recurrent pulmonary emboli. Occlusion of the inferior vena cava was demonstrated in 1 patient and downward displacement of the cava filter in 6 patients. Perforation of at least one prong of the filter through the wall of the inferior vena cava could be recognized in 4 patients. In 1 patient there was fracture of one leg of the filter but this was clinically not apparent.

Adult↗
PubMed1991

Mesh-constricted varicose and dilated veins used as arterial bypass grafts.

To avoid non-autogenous vascular prostheses in coronary and peripheral vascular procedures, otherwise unusable dilated, varicose or thin-walled veins can be implanted as naturally endothelialized grafts after being calibrated by insertion into mesh tubes. In six sheep the 14 mm diameter jugular vein was inserted into a 12 cm long, 6 mm diameter Dacron mesh tube and implanted as a femoropopliteal graft. On the contralateral side the femoral vein with a maximal diameter of 7 to 8 mm was implanted. At control angiography after two months all grafts were patent, none of the wrapped grafts showed wrinkles or signs of anastomotic hyperplasia. Segments of wrapped veins were casted in paraffin under physiological pressure and cut transversely. In all cases the vein wall was pressed against the mesh tubes without forming folds. Mesh-wrapped varicose veins were used for three femorocrural and seven femoropopliteal reconstructions. All grafts showed a smooth flow surface at control angiography. Indentations occurred only at sites where thick-walled side branches had been ligated rather than oversewn. One popliteo-pedal reconstruction occluded after two months and one patient with a crural reconstruction died two months after surgery with a patent graft. The remaining grafts were patent after 11 (2-32) months. Oversized veins can be considerably constricted by tubes without forming wrinkles. By this technique varicose veins can be used as bypass grafts and in general vein grafts can be matched in size to the recipient vessel.

Aged↗
PubMed1991

[Stented dilated or varicose veins as arterial bypass transplants: experimental and initial clinical results].

Dilated and varicose veins are usually not used as arterial bypass-grafts despite they are lined with functional endothelium. External support by a constrictive mesh tube could conform these veins into evenly calibrated bypass-grafts. Ovine jugular veins could be constricted from 15 to 6 mm diameter without forming folds on the inner flow surface. 6 months after implantation of 5 cm long jugular vein segments into the carotid arteries of 7 sheep the inner diameter was 19.5 +/- 3.3 mm for native veins (n = 4) and 7.6 +/- 0.8 mm for constricted veins (n = 10). Intimal hyperplasia was reduced from 0.4 +/- 0.2 mm in native to 0.23 +/- 0.07 mm in reinforced veins (p = 0.03). Mesh tube constricted varicose veins were used as bypass material in 11 infrainguinal reconstructions. All grafts were well calibrated at control angiography. External constriction by mesh tubes is a means to convert varicose veins into suitable bypass grafts.

Aged↗
PubMed1989

[Infrarenal aortic aneurysm: results of surgical treatment].

Between 1976 and 1987 93 patients with an infrarenal aortic aneurysm underwent surgical correction. In 62 patients the procedure was performed electively, whilst 13 displayed an unstable aneurysm and in 18 cases a ruptured aneurysm was present at operation. During the past 5 years the mortality was lowered to 2% in elective cases, whereas in cases of ongoing rupture only moderate improvement took place. The most frequent cause of a lethal outcome was pump failure of the heart (6 times), followed by renal insufficiency and haemorrhagic shock and bleeding complications. Among the non-lethal complications, relaparotomy on the basis of postoperative bleeding ranks first, followed by pulmonary insufficiency, peripheral emboli and partial ischemia of the spine. Resection of infrarenal aneurysms should be performed in the stable state of disease, since insufficiency of multiple vital organ systems increases the mortality by up to 20 fold.

Aged↗
PubMedDate not supplied

Pedal artery bypass.

Pedal artery bypass has proven to be a safe, simple and durable procedure. Failure of a pedal artery reconstruction seldom results in an amputation that is more proximal than it would have been without previous attempted bypass. Thus an aggressive strategy in the revascularisation of the forefoot in case if critical ischemia based on tibial occlusive disease is worthwhile.

Angiography↗