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Biomedical subjects

H Mach

Publications and source records attributed to H Mach.

At least 73 records · Page 4Linked to original sources
PubMed1982

[Cell division and macromolecular synthesis in growing spores of a temperature sensitive filamentous mutant of Bacillus subtilis].

A temperature sensitive mutant of Bacillus subtilis SB 19, strain ts 33-6 was characterized. This strain grows at 46 degrees C (restrictive temperature) with reduced intensity without septation processes. Under restrictive conditions DNA- and RNA-synthesis are remarkably reduced. DNA, however, is synthesized continuously under restrictive conditions causing the formation of multinuclear filaments. Septation, induced at permissive temperature, is not prevented under restrictive conditions. That means that under restrictive conditions initiation of septation is blocked whereas formation of septa can be observed. Shift-up experiments have shown that the initiation of septation processes occurs at an early stage of cell cycle.

Bacillus subtilis↗
PubMed1981

[Synthesis of poly(A)-containing RNA in outgrowing spores of Bacillus subtilis].

The synthesis of poly(A)-containing RNA in outgrowing spores of Bacillus subtilis was studied. A significant amount of RNA puls-labelled with 3H-uridine is polyadenylated. With the beginning of RNA synthesis in outgrowing spores labelled poly(A)-containing RNA was detected. The amount of poly(A)-RNA during the outgrowth and first cell division remains constant. Besides poly(A)-RNA the synthesis of tRNA and rRNA occurs. These results indicate a simultaneous activation of synthesis of tRNA, rRNA as well as of poly(A)-containing RNA during outgrowth of B. subtilis spores.

Bacillus subtilis↗