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Biomedical subjects

H M Windsor

Publications and source records attributed to H M Windsor.

At least 37 records · Page 2Linked to original sources

Calcification of the mitral annulus.

Successful valve replacement has been achieved within the first three years in two patients who had extensive calcification of the mitral valve annulus. This condition, although commonly reported in pathology and autopsy studies, has been rare in our clinical experience. Surgical management does not appear to us to have been reported previously. It was regarded in our earlier experience as a deterrent to mitral valve surgery. Certain technical factors which contributed to success are emphasized in the two cases described in this report.

Calcinosis↗

Coronary artery surgery.

This paper assesses the results in 543 patients undergoing coronary artery surgery between 1969 and March, 1976. Indications included angina, acute infarction and ventricular arrhythmia, and there were some angina-free patients. Surgical techniques were constantly reviewed and frequently changed. The mortality in all groups was 4.2%. The mortality in chronic stable angina (424 cases) was 3%, but as from January, 1975, it has been 2%. The perioperative infarction rate in all groups was 10.7%, and this condition was the most significant cause of perioperative mortality. Modern principles of myocardial protection during surgery have helped to lower mortality and morbidity rates.

Coronary Artery Bypass↗

Right coronary endarterectomy: a procedure with increased risk of perioperative infarction.

Although right coronary endarterectomy extends operability on this vessel, the procedure is associated with increased risk of perioperative infarction. Forty-nine patients at St Vincent's Hospital underwent endarterectomy and saphenous vein grafting to the distal right coronary artery, with a hospital mortality of 6.1% and a perioperative infarction rate of 20.4%, compared with rates of 4.2% and 10.9% respectively in a group of patients who did not require endarterectomy. These figures show a trend toward statistical significance which suggests that careful patient selection for endarterectomy is required to obviate an increased risk of complications with this procedure.

Coronary Artery Bypass↗

Left main coronary artery obstruction: early surgical experience with forty-two patients.

Direct coronary artery surgery was performed on 42 patients with high grade obstruction of the left main coronary artery (LMCA), with a perioperative infarction rate of 7% and a hospital mortality of 9-6%. There was no significant difference in presentation of patients with LMCA lesions and no prediction of this lesion could be made by preangiographic assessment. Significant obstructive lesions in other coronary vessels were noted in most patients, triple vessel disease occurring in 27 patients (64-3%), double vessel in 14 patients (33-3%) and the LMCA lesion was an isolated lesion in only one patient (2-4%). Right coronary lesions occurred in 35 patients (83%), left anterior descending artery artery lesions in 38 patients (90%) and left circumflex system lesions in 34 patients (81%). The surgical procedures are discussed.

Acute Disease↗

Post-infarction cardiac rupture.

Three allied conditions are described in this paper: (i) haemopericardium with cardiac rupture (5 cases); (ii) haemopericardium without rupture (2 cases); (iii) pseudoaneurysm (1 case). In the first 2 of these, the significant features were clinical deterioration with shock 3 or more days after infarction, recurrent cardiac pain, cardiac tamponade, and immediate or later ineffectiveness of counterpulsation. An additional feature in the second group was the development of haemopericardium after heparin therapy. In the third group, infarction followed by left ventricular failure and progressive cardiac enlargement was the significant feature. An apical systolic murmur was not present, as a false sac had not been formed. Ante-mortem diagnosis depends upon an appreciation of these features. Without it successful surgery is impossible. There were 4 survivors in this group of 8 patients.

Aged↗

Tracheal injury following prolonged intubation.

Prolonged respiratory assistance by positive pressure ventilation via cuffed tracheostomy or endotracheal tube can be complicated by mucosal erosions, tracheal stenosis, tracheomalacia, excavation of the tracheal wall with loss of tissue and tracheoesophageal fistula. Stenosis can occur at the subglottic region, at the stoma, or at the cuff site, whereas the other complications occur most often at the cuff site. This paper is concerned with complications occurring below the first tracheal ring.

Adolescent↗

Acute severe cardiac failure complicating myocardial infarction. Experience with 100 patients referred for consideration of mechanical left ventricular assistance.

One hundred patients were referred with suspected acute cardiac failure following acute myocardial infarction. The diagnosis was confirmed in 72: 31 of these patients underwent elective medical treatment, with 2 survivors (6%); 41 were accepted for counter pulsation, but 9 died before this could be initiated and another 2 died shortly after vain attempts to pass the balloon catheter were abandoned; 30 patients underwent counterpulsation with 14 hospital survivors (47%). Survivor status was usually good. Results of counter pulsation were better in patients who were not shocked (with 5/5 survivors) than in those who were in shock (with 9 of 25 survivors). Results support the view that counterpulsation (alone or combined with corrective surgery) may play an important role in the complications of myocardial infarction provided intervention is early.

Acute Disease↗