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Biomedical subjects

H M Terblanche

Publications and source records attributed to H M Terblanche.

12 recordsLinked to original sources
PubMed1983

Clinical and endocrine studies during normal and induced parturition in mares.

Parturition was induced in 6 mares between Day 327 and 346 of pregnancy using oxytocin (Group I) and in 6 mares between Day 315 and 330 of pregnancy with fluprostenol in combination with oxytocin (Group II). A third group of 4 mares which served as controls were allowed to go to full term (322-340 days) and foal down normally. Parturition occurred within 24-102 min (mean = 61,4; SD = 31,6) in 5 of the Group I mares and within 160-185 min (mean = 173; SD = 10,86) in the mares of Group II. Expulsion of the afterbirth took place between 7 and 206 min (mean = 79; SD = 76,38) and between 7 and 73 min (mean = 37,5; SD = 21,29) in Groups I and II respectively. Three of 6 mares in the oxytocin group showed foal heat, all 3 conceived and 2 carried foals to term. Of the remaining 3 mares, 2 showed heat approximately one month after parturition, and were served and conceived but one aborted due to babsesiosis and one resorbed while the third remained in anoestrus for 3-4 months. In the combined treatment group, 3 mares showed foal heat of which only 2 were served. Both conceived and one carried a foal to term. One of the remaining mares showed oestrus 2 months after parturition while the remaining 2 mares showed oestrus approximately one month after parturition. Both were served, one conceived but subsequently resorbed.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1981

Plasma progesterone levels in the mare during the oestrous cycle and pregnancy.

Plasma progesterone was determined with the aid of a competitive protein-binding assay in mares during the oestrous cycle, early pregnancy (45--60 days) and later pregnancy (2--10 months). Progesterone levels were low during oestrus (less than 1 ng per ml) (3,18 nmol/l) and reached high levels (often in excess of 10 ng per ml) (31.8 nmol/l) within 3--4 days after ovulation. The high luteal levels were maintained for approximately 5--8 days and then declined sharply over a period of approximately 24--48 hours to reach low levels at the subsequent oestrus period. In mares conceiving after service, the progesterone levels rose rapidly to 5--9 ng per ml (15,9--28,6 nmol/l) 21 days after service. Levels of 4--10 ng per ml (12,7--31,8 nmol/l) were found between 30 and 60 days after successful service with a tendency towards lower levels from 30--42 days and higher levels from 42--60 days. Progesterone levels remained between 7 and 10 ng per ml (22,3--31,8 nmol/l) from 60--110 days and thereafter fell to a relatively constant level of 3--6 ng pe ml (9,5--19,1 nmol/l) until the tenth month of pregnancy.

Animals↗
PubMed1981

Plasma progesterone in cattle. II. Levels during the oestrous cycle, pregnancy and parturition.

Plasma progesterone was determined in cattle with a competitive protein binding assay during the oestrous cycle, pregnancy and parturition. Peak luteal phase levels of 4--7 ng/ml (12,7--22,2 nmol/l) were found 12--16 days after clinical oestrus followed by a rapid decline to less than 0,5 ng/ml (1,6 nmol/l) on the day of oestrus. Levels of 3--7 ng/ml (9,5--22,3 nmol/l) were found 3 weeks after artificial insemination while levels of 3,8--6,5 ng/ml (12,1--20,7 nmol/l) and 3--7 ng/ml (9,5--22,3 nmol/l) were found at 6 and 7--8 weeks respectively. Between the second and third month of pregnancy levels of 3,5--6,5 ng/ml (11,1--20,7 nmol/l) were measured increasing to 3--8 ng/ml (9,5--25,4 nmol/l) from the fifth month until shortly before parturition. Levels of approximately 3--4 ng/ml (9,5--12,7 nmol/l) were found until 3 d before parturition with a drop to 2 ng/ml (6,4 nmol/l) 1 d before calving. Less than 1 ng/ml (3,2 nmol/l) was measured on the day of parturition and during the first 3 d after calving.

Animals↗
PubMed1980

Induced parturition in cattle. II. Plasma oestrogen and progesterone levels.

Plasma oestrogen and progesterone levels were determined in cattle at the time of dexamethasone induced parturition. Oestrogen levels were elevated from the day after dexamethasone administration as well as on the day of parturition but declined rapidly to low levels on the day following parturition. Progesterone levels showed a decrease from the day of dexamethasone administration until parturition with a rapid drop to very low levels on the day following calving. These results are similar to those reported by other workers.

Animals↗
PubMed1980

[Use and misuse of hormones in female reproductive disorders].

The correct use of hormones in genesiological cases is discussed with indications for their use, dosage levels and duration of treatment under the following groups, viz. hypothalamic hormones, hypophyseal hormones, other gonadotrophins, steroids, combinations of the foregoing and prostaglandins. The more important dangers associated with hormone therapy are then briefly discussed with a few examples of the more common and hazardous abuses.

Adrenal Cortex Hormones↗
PubMed1980

Plasma progesterone in cattle. I. Development and validity of the assay.

The development of a practical competitive protein-binding assay for plasma progesterone in cattle is described. With an intra-assay coefficient of variation of 5,46% and an interassay coefficient of variation of 14,25%, the method is sufficiently accurate and sensitive for practical purposes, and for use in routines and surveys. The statistical level of sensitivity was found to be in the region of 0,25 ng/ml based on the confidence limits of zero dose and 0,25 ng/ml, with the practical sensitivity level at 0,50 ng/ml. Method and reagent blanks were found to be negligible. The specificity of the assay is based entirely on the partial specificity of the petroleum ether used for the extraction of progesterone (87,5% extraction, n = 141).

Animals↗
PubMed1976

Induced parturition in cattle. 1. Clinical studies.

Parturition was induced in 17 Friesland heifers to decrease the possible occurrence of dystocia. The heifers were given 39 mg dexamethasone intra-muscularly on the 267th day of pregnancy and were observed for signs of impending parturition. The time of foetal membrane expulsion was noted. Parturition occurred on an average of 57 hours after corticosteroid administration. Three heifers required assistance during parturition. In one case a second injection of dexamethazone had to be given. The incidence of retained placenta was 68,8%. Rectal examination five to seven months after induction revealed that 76,5% of all animals were again pregnant. Of the four non-pregnant animals three had received assistance during parturition.

Animals↗