Nicotinic and muscarinic activity of benzyltrimethyl-ammonium and its alpha-, beta- and gamma-substituted pyridylmethyltrimethylammonium analogs.
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Biomedical subjects
Publications and source records attributed to H M Rubinstein.
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Two brothers with Thiemann's disease are described and the accumulated world literature is briefly reviewed. Thiemann's disease is considered to be a form of idiopathic avascular necrosis of the PIP joints of the hands, with occasional involvement of other joints. The characteristic deformity and x-ray findings are reviewed. Thiemann's disease is a genetic disorder and, in families in which detail is available, is inherited as an autosomal dominant with virtual complete penetrance.
Twenty-seven patients with thirty-six joints affected with acute gouty arthritis were treated with fenoprofen calcium for a duration not exceeding 8 days and with a variable dose not exceeding 3.2g daily. The results indicated that fenoprofen calcium was an effective drug in these patients. Side effects were modest.