Acute respiratory distress syndrome in a premature calf.
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Biomedical subjects
Publications and source records attributed to H M Pirie.
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The mucosubstances of the bronchial epithelial goblet cells in non-pneumonic calves were almost exclusively sulphomucin; neutral mucin, sialomucin and sulphomucin were produced by the submucosal glands. Calves with lesions of cuffing pneumonia from which M. dispar was frequently cultured had increased numbers of epithelial goblet cells extending into the peripheral airways as far as the bronchioles. These pneumonic animals had epithelial goblet cells, some of which contained sialomucin, while in the gland a switch from neutral to acid mucosubstance in the form of increased sulphomucins and sialomucins was detected.
The tracheobronchial mucosubstances in a group of normal dogs and a group of dogs with chronic bronchitis have been characterized histochemically. Sulphomucin was the predominant mucosubstance in the epithelial goblet cells of normal dogs and a mixture of sulphomucin and sialomucin was found in the bronchial glands. In the dogs with chronic bronchitis there was a shift towards the production of sialomucin in both sites.