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Biomedical subjects

H M Perkins

Publications and source records attributed to H M Perkins.

12 recordsLinked to original sources
PubMed1978

Epidural injection of local anesthetic and steroids for relief of pain secondary to herpes zoster.

We treated 12 cases of cutaneous herpes zoster (HZ) with epidural bupivacaine and methylprednisolone acetate. Treatment was effective for HZ of less than seven weeks' duration. The course of HZ of greater than three months' duration (postherpetic neuralgia) was not improved. The administration of epidural bupivacaine plus methylprednisolone acetate was no more effective than when bupivacaine alone was used. Epidural injection of bupivacaine with or without methylprednisolone acetate is the treatment of choice for the pain of cutaneous HZ.

Adult↗
PubMed1978

Effects of high ambient temperature on sleep in young men.

Each of 10 normal subjects had 4 nights of laboratory-monitored sleep, consisting of adjustment, baseline, high blanket temperature (HBT), and recovery nights. EEG-EOG recordings were made on each night; rectal temperature, heart rate, body weight, and ambient temperatures were monitored throughout the last 2 nights. On the HBT night, subjects had less total sleep time, more frequent and longer awakenings, greater shifting among sleep stages, decreased amounts of stage 1 REM and stages 3 + 4, and delayed onset of deep sleep (stages 3 and 4). Body temperature was elevated to a relatively constant level of 37 degrees C on the HBT night, but gradually decreased from 36 degrees C to 34.5 degrees C across the recovery night. Heart rate decreased at a linear rate on both the HBT and recovery nights, but was 15 beats/min faster on the former. Subjects experienced liquid loss of 1.25 kg on the HBT night, but had a full recovery by the following evening.

Adult↗