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Biomedical subjects

H M Hodkinson

Publications and source records attributed to H M Hodkinson.

At least 55 records · Page 3Linked to original sources

Red-blood-cell potassium and hand-grip strength in healthy elderly people.

Red-blood-cell potassium (RBCK) as an indicator of body potassium status was measured in 103 healthy elderly subjects over the age of 65 years. There was no correlation between RBCK and grip strength. The only significant predictors of grip strength were age and sex. The RBCK values formed a single normal distribution. There was no hypokalaemic subpopulation such as would be expected if potassium deficiency were common in these old people.

Age Factors↗

Causes of high free-thyroxine index values in sick euthyroid elderly patients.

Modest elevation of the free-thyroxine index occurs in many apparently euthyroid elderly in-patients. The present study investigated the possible relevance of drug side-effects to this problem. It appears that such side-effects associated with the use of L-Dopa, digoxin and co-trimoxazole account for a substantial proportion of the observed elevated free-thyroxine index results.

Atrial Fibrillation↗

Screening for hypothyroidism in elderly inpatients.

Routine biochemical screening for hypothyroidism in 2000 geriatric inpatients proved valuable and practicable and yielded 46 cases (2.3%). A non-specific clinical picture was particularly common, with less than a third of the cases showing "typical" signs and symptoms. Psychiatric manifestations, especially depression, were important and frequent and responded well to thyroxine. There was a preponderance of female cases of hypothyroidism and a strong association with other autoimmune diseases, notably pernicious anaemia and rheumatoid arthritis.

Aged↗

Glomerular filtration rate in sick elderly inpatients.

The glomerular filtration rate was measured in the sick elderly patients using the single shot 51Cr EDTA method. As would be expected, such patients have worse renal function than the fit elderly. The filtration rate can be usefully predicted from either blood urea or serum creatinine, but a superior prediction is obtained when these factors are combined using a formula derived from multiple regression analysis.

Aged↗

Unilateral clubbing in hemiplegia.

A study of clubbing, assessed by spherometer measurements of fingernail-skinfold angle, was made in recent and long-established hemiplegic elderly patients. This showed that clubbing developed in all digits studied and that it increased with the duration of the stroke. Clubbing did not correlate with the grip strength of the weakened hand.

Adult↗