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Biomedical subjects

H M Goldstein

Publications and source records attributed to H M Goldstein.

At least 55 records · Page 3Linked to original sources

Colonic polyp detection: role of roentgenography and colonoscopy.

In order to determine the relative yields of colonoscopic and radiologic examinations of the colon, the following guidelines are suggested: (a) prospective data collection; (b) a standard, effective colon cleansing regimen; (c) colonoscopic and radiologic examiners of comparable expertise; (d) examiners should be unaware of each other's findings; (e) a suitable method for demonstrating false-negative findings and for resolving conflicting findings between the two examinations; and (f) indexing of the study findings as to lesion size, lesion location, quality of colon cleansing, and examiner's level of confidence. The two examinations should be used as complementary diagnostic procedures.

Colon↗

Radiologic manifestations of esophageal lymphoma.

Eight cases of esophageal lymphoma are presented. Contiguous involvement of the distal esophagus and stomach with narrowing and/or nodularity was the most common esophageal abnormality. Other appearances noted were an ulcerated mass, multiple submucosal nodules, and a pattern simulating varices. The spectrum of radiologic appearances with esophageal lymphoma is similar to lymphomatous involvement in the remainder of the gastroinestinal tract.

Adult↗

Radiologic spectrum of opportunistic infections of the upper gastrointestinal tract.

Clinical findings and barium studies were reviewed in 34 patients with upper gastrointestinal opportunistic infections, including two with gastric involvement. The spectrum of radiologic features is presented with particular attention to early subtle findings such as disturbance of esophageal motility and tiny marginal filling defects. While most cases are due to Candida albicans, other organisms may also invade the upper gastrointestinal tract in the debilitated host.

Adult↗

Gray scale ultrasonography of calcified liver metastases.

Three cases of calcified liver metastases demonstrating acoustical shadowing on gray scale ultrasonography are reported. Ultrasonography may show calcified liver masses that are not readily apparent on plain film radiographs. The discovery of calcified liver metastases by ultrasound can suggest a primary site of malignancy.

Calcinosis↗

Primary ulcerative carcinoma of the esophagus.

Six patients with primary ulcerative carcinoma of the esophagus are described. The radiologic appearance is analogous to the Carman-Kirklin complex seen with gastric malignancies. The clinical course of this uncommon type of esophageal carcinoma is the same as the more common constricting and polypoid varieties.

Aged↗

Radiologic spectrum of melanoma metastatic to the gastrointestinal tract.

Radiologic experience in 67 patients with melanoma metastatic to all portions of the gastrointestinal tract is reviewed. Besides the well known "bull's-eye" lesion of the upper gastrointestinal tract, a large variety of radiologic presentations of melanoma metastases is discussed and illustrated. Because of extended survival due to improved chemotherapy and immunotherapy, the importance of careful radiologic examination of the melanoma patient is stressed.

Biliary Tract Diseases↗

Cavitating metastases of the small intestine.

Ten patients with small intestinal excavating metastatic lesions are described. Cavitation of a mass is a generally unrecognized appearance of metastatic disease to the small intestine and should be considered in the differential diagnosis of small bowel excavation.

Adult↗

Ultrasonography in tumors arising from the spine and bony pelvis.

Gray scale ultrasonography is a useful tool in evaluating pelvic and abdominal soft tissue masses that may be associated with bone neoplasms. Four patients are described: two with giant cell tumors, one with Ewing's sarcoma, and one with a sacrococcygeal teratoma. Ultrasound is especially helpful in assessing the extent of disease, treatment planning, and in following the results of therapy.

Adolescent↗

Double-contrast examination of the esophagus.

A simple technique for double-contrast esophagography is described. The technique involves successive swallows of an excellent coating barium mixture and water to create the double contrast effect. Clinical and radiologic situations in which double contrast esophagography have proven helpful include: (a) the detection of small esophageal tumors; (b) delineation of the morphologic features of neoplastic and inflammatory disease; and (c) assessment of the total vertical extent of esophageal disease. Accurate and/or confident diagnosis is aided considerably with double-contrast esophagography.

Barium Sulfate↗

Intravascular occlusive therapy: use of interventional radiology in cancer patients.

Selective transcatheter intravascular occlusion in the treatment of cancer patients is a valuable extension of interventional diagnostic radiology. Intra-arterial embolization may be performed with various substances, including autologous clot, autologous subcutaneous tissue, Gelfoam, and stainless steel coil. Clinical applications in cancer patients include control of gastrointestinal and genitourinary hemorrhage, preoperative reduction of tumor vascularity, control of local symptoms, and therapeutic reduction of tumor bulk. The technique has been used for preoperative and palliative treatment of neoplasms of the head and neck, kidney, liver, spleen, and soft tissue and bone. Transcatheter intravascular occlusion should be performed only by radiologists experienced in angiographic techniques. Inadvertent occlusion of a normal vessel and thromboembolism are possible complications.

Angiography↗

Priscoline-augmented hepatic angiography.

Tolazoline hydrochloride (Priscoline) is a useful adjunct to hepatic angiography in the evaluation of space-occupying lesions. It was of definite value in 8 of 26 studies, either in facillitating the diagnosis or in evaluating the extent of disease. The mechanism of enhanced visualization is presumably related to its vasodilatory effect on the small blood vessels of the liver. Priscoline deserves further evaluation in the following situations: (a) a negative hepatic angiogram in the face of positive clinical findings or radionuclide images; (b) suspicious but not definitive findings on conventional hepatic angiography; and (c) assessment of the full extent of disease.

Adult↗

Transcatheter occlusion of abdominal tumors.

Radiological and clinical experience with transcatheter intravascular occlusion of abdominal and pelvic tumors in 55 patients is presented. Major indications include control of hemorrhage, palliation of local tumor symptoms, and preoperative management of facilitate surgery. Methods of occlusion included embolization (clot, subcutaneous tissue, and Gelfoam), introduction of a stainless steel coil into larger vessels, and balloon catheters. Hemorrhage was controlled in 8 of 12 patients with bleeding gastrointestinal and pelvic tumors. Experience in 36 patients with hypernephroma is discussed. Initial observations are presented, including occlusion of the hepatic artery for dearterialization of primary and secondary neoplasms and of the splenic artery for hypersplenism.

Abdominal Neoplasms↗

Azygography in the pre-treatment evaluation of oesophageal carcinoma.

Azygography is a useful technique for the pre-operative detection of unresectability of oesophageal malignancies. Invarison of the azygos vein by oesophageal carcinoma occurs because of the anatomic proximity of the thoracic oesophagus and the azygos vein. Azygography may be performed by either intraosseous injection of a rib or by direct retrograde catheterization. Complete obstruction of the azygos vein indicates that an oesophageal carcinoma is unresectable if no other intrathoracic disease is evident.

Angiography↗

Air contrast colon examination in patients with colostomies.

A readily feasible technique for producing an excellent air contrast examination of the colon in patients with colostomies is described. The technique employes no special equipment and is easily tolerated by patients. Indications for the examination include a symptomatic patient with a negative conventional enema or suspicious single column examination. The surprisingly high incidence of both benign and malignant coexisting colonic neoplasms is reviewed.

Aged↗

Treatment of symptomatic hepatic cyst by percutaneous instillation of Pantopaque.

A large, symptomatic, simple hepatic cysts was managed by the percutaneous instillation of Pantopaque. The method was based on reports of similar percutaneous treatment of renal cysts. In 6 months the patient was asymptomatic and radiographs demonstrated evidence of a fibrous reaction within the cyst. The patient remains asymptomatic 16 months after puncture. These results suggest that percutaneous instillation of sclerosing agents may provide an alternative to operative procedures.

Cysts↗

Transcatheter embolization of the internal iliac artery in the management of neoplasms of the pelvis.

Six patients with neoplasms of the pelvis were treated with embolization of the internal iliac artery. The technique was used for the control of hemorrhage and pain and for preoperative devascularization. No complications or serious side-effects occurred. Embolization of the internal iliac artery often provides a therapeutic alternative, when a surgical procedure is not feasible.

Adult↗