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Biomedical subjects

H M Eriksen

Publications and source records attributed to H M Eriksen.

At least 91 records · Page 5Linked to original sources
PubMed1980

Chemical plaque control and extrinsic discoloration of teeth.

Extrinsic discoloration of teeth is an unwanted side-effect in connection with the use of the chemical plaque-preventive agent chlorhexidine. Individual differences in discoloration tendency have, however, been observed. In order to study the nature of these extrinsic discolorations a selection of 3 typical "stainers" and 3 "non-stainers" was made based on the individual tendency to develop extrinsic discolorations of teeth after a ten days rinsing with 0.2% chlorhexidine twice a day. The individual discoloration tendency was maintained through various plaque-preventive regimens. Interference with the retention of chlorhexidine by a cation demonstrated a close correlation between antiplaque activity and the discoloration tendency. A commercial oxidizing agent based on peroxy monosulfate showed the most promising properties in reducing this extrinsic discoloration without interfering with plaque-prevention.

Bacteria↗
PubMed1980

Indirect clinical methods for evaluation of resin filling materials.

The importance of a correlation between quality data and reasons for replacement of dental restorations is emphasized. For composite resins, deterioration of the marginal adaptation seems to be the single most dominating reason for replacement followed by recurrent caries and general discoloration. A comparison of direct and indirect clinical techniques is made and benefits and shortcomings are discussed. In conclusions direct visual inspection is recommended for extensive survey studies while indirect procedures may be suitable in smaller and more discriminatory experimental investigations.

Chemical Phenomena↗
PubMed1979

Tooth stain during 2 years' use of chlorhexidine- and fluoride-containing dentifrices.

The purpose of the present study was to evaluate the effect of fluoride upon the stain-inducing capacity of chlorhexidine. Ninety-one children, 13 years of age, volunteered for the experiment. Three test dentifrices were used, containing 0.1% NaF, 0.1% NaF + 2% chlorhexidine, and 2% chlorhexidine respectively. The experiment was carried out as a double-blind test, and the degree of staining was recorded after 1 and 2 years. Four methods were used for stain scoring. The results after 1 year showed that chlorhexidine induced less stain when applied together with fluoride than when applied alone. After 2 years this difference disappeared, indicating that fluoride only retarded chlorhexidine-induced staining of teeth.

Adolescent↗
PubMed1979

Monkey pulpal response to composite resin restorations in cavities treated with various cleansing agents.

Pulpal response to composite resin restorations placed in experimentally prepared cavities treated with various cavity cleansing and etching agents were studied in monkey teeth. The use of etching agents and cleansers with a demineralizing potential enhanced the pulpal response to composite resin restorations. Bacterial proliferation on the cavity walls around the composite restorations may be one of several factors causing the harmful pulpal responses found. The protective effect of a calcium hydroxide-containing cavity lining material was confirmed.

Acid Etching, Dental↗
PubMed1979

Affinity of hydroxyapatite for furfural and a brown pigment formed by furfural and glycine.

The affinity of hydroxyapatite for furfural and a brown pigment formed by furfural and glycine was studied. A series of mixtures containing 1 M furfural and 0.25-2.0 M glycine were incubated at 37 degrees C and aliquots of hydroxyapatite added. The apatite showed a strong affinity for the brown pigment formed, and an excess of glycine in the mixtures appeared to enhance the binding. The adsorption of furfural to hydroxyapatite was estimated by a spectrophotometric method. The data revealed that pretreatment with CaCl2 and glycine significantly increased the adsorption of furfural.

Adsorption↗
PubMed1979

A scanning electron microscopic study of the effect of various cleansing agents on cavity walls in vitro.

The appearance of prepared cavity walls after treatment with different cavity cleansers and cleaning procedures was studied. Class II and V cavities were prepared on extracted human and monkey teeth and the cavities were exposed to the different agents for 1 min. Where commercial products were used, the manufacturers' directions for use were followed. The cavity walls were examined in the scanning electron microscope and representative photos were taken from dentinal and enamel areas. Only demineralizing solutions producing an etch pattern were able to remove the smeared layer from the cavity walls.

Animals↗
PubMed1979

Microleakage along composite restorations in human premolars after treatment with different cleansing agents.

Cavities prepared on extracted human premolars wereeee treated with different cleansing agents and by different procedures. The cavities were filled with a composite restorative material and microleakage was assessed by recording the penetration of basic fuchsin dye. Only acid agents which removed the smeared layer, producing an etch pattern on the enamel cavity walls, were able to prevent microleakage.

Bicuspid↗
PubMed1979

Evaluation of extrinsic tooth discoloration.

Extrinsic brown tooth discolorations are frequently detected in connection with antibacterial agents used for chemical plaque control. The present investigation confirmed the staining ability of an antibacterial quarternary ammonium salt, benzethoniumchloride, used as a 2% additive to a dentifrice. A weak chelator did not alter the discoloration tendency. Extrinsic discoloration was evaluated both by direct inspection, from color photographs and by using a microphotometric technique. The discoloration tendency was well demonstrated by all three techniques. Evaluation from the color photographs, however, may be preferable in epidemiological surveys while the microphotometric technique may possess certain advantages in detailed experimental discoloration studies.

Adult↗
PubMed1978

In vitro caries related to marginal leakage around composite resin restorations.

The histology of caries-like lesions around composite resin restorations with and without marginal leakage has been studied. The lesions were generated from bacterial plaque growing in an in vitro system. Marginal leakage was prevented by an acid etch technique. Ground sections of the experimental teeth were studied by polarized light and microradiography. The caries lesions penetrated along conventional class V restorations with marginal leakage while restorations bonded to an acid etched enamel surface totally prevented this ingrowth.

Acid Etching, Dental↗
PubMed1978

Extrinsic discoloration of teeth.

The majority of tooth discolorations are extrinsic in nature and appear as brown integuments. Various clinical indices and photometric techniques have been used for the evaluation of extrinsic discolorations. Smoking, tea or coffee consumption and increasing age are promoting factors and such discolorations are frequently seen in connection with oral use of antibacterial plaque-inhibiting mouthrinses. Chemical alteration of the acquired pellicle appears to be the major reason for these brown integuments.

Age Factors↗
PubMed1978

Reasons for replacement of amalgam dental restorations.

Recurrent caries appears to be the most frequently occurring reason for replacement of amalgam dental restorations. Recent developments of amalgam alloys have improved the clinical appearance of such fillings but the possible influence on their durability is uncertain.

Dental Amalgam↗
PubMed1978

Lactate dehydrogenase (LDH) isoenzyme pattern in normal and inflamed human dental pulp.

Enzyme variants may serve an adaptive role in providing the correct vectorial properties for the metabolism of a tissue, or broadening its environmental tolerance range. To determine if the LDH isoenzyme pattern of human dental pulp changes during inflammation, supernatants from normal and inflamed dental pulp homogenates were separated by polyacrylamide gel electrophoresis. Inflamed pulps had a higher M subunit content and a markedly increased enzyme activity. These results might reflect adaptive changes at the enzyme level associated with a partial shift towards anaerobic metabolism during inflammation of the pulp.

Adult↗
PubMed1977

A comparison of the plaque-inhibiting effect of stannous fluoride and chlorhexidine.

A double blind clinical trial was undertaken in order to compare the plaque inhibiting effect of SnF2 (0.2% and 0.3%) with chlorhexidine (0.1%) applied as mouthrinses in a test panel of 12 dental hygienist students. The experimental series were performed in periods of four days. The mean Plaque Index values were 0.35 and 0.2 when employing SnF2 and 0.1 when chlorhexidine was used, whereas distilled water resulted in a mean value close to 1.0. The long-term effect of a 0.3% SnF2 solution was tested in another group of five students for a period of three weeks. The two trials confirmed previous reports claiming that SnF2 is effective as a plaque inhibitor and, furthermore, that this effect could be maintained for a period of at least three weeks. The staining problem was less than in similar studies using chlorhexidine.

Biguanides↗
PubMed1977

Biologic assessment of copper-containing amalgams.

In order to reduce creep and avoid marginal fractures in amalgam restorations, new alloys containing higher proportions of copper have been introduced. Fillings of these materials were placed in cavities prepared in the deciduous teeth of monkeys or placed in polyethylene tubes and implanted subcutaneously in rats. Conventional silver/tin alloys and zinc oxide eugenol cement were used as reference materials. Despite limitations due to the varying depths of cavities and the small number of animals involved it was concluded that the high copper alloys caused more severe pulp damage than the other materials studied. In the implantation studies many of the high copper specimens were exfoliated before the end of the experimental period. It is concluded that in deep cavities these materials require the use of a non-toxic base or lining material although as they are commonly used in young children's teeth the placement of linings and the isolation of the cavity pose problems.

Animals↗